PPOX
protoporphyrinogen oxidase
Synonyms:
PPO, V290M, VP
Species:
Human PPOX (5498), Mouse Ppox (19044), Rat Ppox (289219), fruit fly Ppox (42939), naked mole-rat Ppox (101703782), Thale Cress PPOX (827991), Zebrafish ppox (664750), dog PPOX (478980), domestic cat PPOX (101090326), cow PPOX (515770) ...More
UniProtKB ID:
Gene ID:
- Human(5498) Summary: This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
- Mouse(19044) protoporphyrinogen oxidase
- Rat(289219) protoporphyrinogen oxidase
- fruit fly(42939) Protoporphyrinogen oxidase
- naked mole-rat(101703782) protoporphyrinogen oxidase
- Thale Cress(827991) protoporphyrinogen oxidase
- Zebrafish(664750) protoporphyrinogen oxidase
- dog(478980) protoporphyrinogen oxidase
- domestic cat(101090326) protoporphyrinogen oxidase
- cow(515770) protoporphyrinogen oxidase
- Horse(100066168) protoporphyrinogen oxidase
- sheep(101103440) protoporphyrinogen oxidase
- Domestic Rabbit(100340158) protoporphyrinogen oxidase
- domestic guinea pig(100735630) protoporphyrinogen oxidase
- Thale Cress(835061) pyridoxine/pyridoxamine 5'-phosphate oxidase 1
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