Merck
  • Home
  • Search Results
  • A new look at old agents for pleurodesis: nitrogen mustard, sodium hydroxide, and silver nitrate.

A new look at old agents for pleurodesis: nitrogen mustard, sodium hydroxide, and silver nitrate.

Current opinion in pulmonary medicine (2000-07-27)
F S Vargas, A O Carmo, L R Teixeira
ABSTRACT

In this review we analyze the evolution of pleurodesis. In spite of the fact that this procedure started in the beginning of the 20th century, the ideal sclerosing agent is not yet known. Emphasis is placed on the current tendency toward minimally invasive procedures in which insertion of catheters is favored over surgical procedures such as placement of chest tubes or thoracoscopy. Among the sclerosing agents, talc is preferred throughout the world. However, the possible development of acute respiratory distress syndrome, which is sometimes fatal, caused the awakening of interest in other drugs. Nitrogen mustard induces pleurodesis but causes important side effects. Sodium hydroxide and silver nitrate are effective and may be used in humans beings.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Silver nitrate on silica gel, extent of labeling: ~10 wt. % loading, +230 mesh
Sigma-Aldrich
Silver nitrate solution, 2.5 % (w/v) AgNO3 in H2O
Sigma-Aldrich
Ascarite®, Sodium hydroxide-coated silica, 20-30 mesh
Sigma-Aldrich
Ascarite®, Sodium hydroxide-coated silica, 8-20 mesh
Sigma-Aldrich
Sodium hydroxide solution, 1.0 N, BioReagent, suitable for cell culture
Sigma-Aldrich
Silver nitrate, BioReagent, suitable for plant cell culture, >99% (titration)
Sigma-Aldrich
Silver nitrate, BioXtra, >99% (titration)
Sigma-Aldrich
Silver nitrate, 99.9999% trace metals basis
Sigma-Aldrich
Silver nitrate, tested according to Ph. Eur.
Sigma-Aldrich
Sodium hydroxide, BioUltra, for luminescence, ≥98.0% (T), pellets
Supelco
Sodium hydroxide solution, 49-51% in water, eluent for IC
Sigma-Aldrich
Sodium hydroxide solution, BioUltra, for molecular biology, 10 M in H2O
Supelco
Sodium hydroxide concentrate, 0.1 M NaOH in water (0.1N), Eluent concentrate for IC
Sigma-Aldrich
Silver nitrate, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.8%
Sigma-Aldrich
Sodium hydroxide, pellets, semiconductor grade, 99.99% trace metals basis
Sigma-Aldrich
Sodium hydroxide, ACS reagent, ≥97.0%, pellets
Sigma-Aldrich
Sodium hydroxide, reagent grade, 97%, flakes
Sigma-Aldrich
Sodium hydroxide, beads, 20-40 mesh, reagent grade, 97%
Sigma-Aldrich
Sodium hydroxide solution, 50% in H2O
Sigma-Aldrich
Sodium hydroxide, ultra dry, powder or crystals, 99.99% trace metals basis
Sigma-Aldrich
Sodium hydroxide, reagent grade, 97%, powder
Sigma-Aldrich
Sodium hydroxide, reagent grade, ≥98%, pellets (anhydrous)
Sigma-Aldrich
Sodium hydroxide, puriss. p.a., ACS reagent, K ≤0.02%, ≥98.0% (T), pellets
Sigma-Aldrich
Sodium hydroxide solution, 5.0 M
Sigma-Aldrich
Silver nitrate, ReagentPlus®, ≥99.0% (titration)
Sigma-Aldrich
Silver nitrate, meets analytical specification of Ph. Eur., BP, USP, 99.8-100.5%
Sigma-Aldrich
Sodium hydroxide solution, purum, ≥32%
Sigma-Aldrich
Silver nitrate, puriss. p.a., ≥99.5% (AT)
Sigma-Aldrich
Silver nitrate, ACS reagent, ≥99.0%
Sigma-Aldrich
Sodium hydroxide, puriss. p.a., ACS reagent, reag. Ph. Eur., K ≤0.02%, ≥98%, pellets