Skip to Content
Merck
HomeProductsPharma & Biopharma ManufacturingBioprocessing & Formulation Raw Materials

Bioprocessing & Formulation Raw Materials

Endonuclease enzymes

Process chemicals are key components for biopharmaceutical manufacturing. High-quality products, comprehensive documentation, and superior customer support facilitate your efforts in qualification, risk assessment, and process optimization to make your process development and manufacturing a success. Satisfy your regulatory requirements via our Emprove® Program for the full range of products spanning the entire biomanufacturing process. 

Endonuclease enzymes

Endonuclease

Endonuclease enzymes are used to reduce the level of nucleic acid contamination in bioprocessing workflows and research applications by cleaving DNA and RNA into smaller fragments.

Buffers & pH Adjusters

Buffers play a critical role in controlling pH in all phases of bioprocessing including cell banking, upstream, downstream, and final formulation. We offer the full range of organic and inorganic buffer components.

Three containers of varying sizes for storing buffers and pH adjusters, with the smallest on the left and the largest on the right

Explore More Categories

Technician in a cleanroom suit handling liquid cell culture media in a bioprocessing laboratory, with neatly arranged rows of sealed bottles containing the media and essential lab equipment in the background, indicating a sterile and controlled environment for bioprocessing applications.
Bioprocessing Liquid Cell Culture Media & Buffers

We offer the industry’s highest quality sterile filtered liquid capabilities, supplying ready-to-use cell culture media, buffers, CIP and SIP products from GMP facilities worldwide to optimize your biopharma production.

View Products
Technician overseeing bioreactor for chemical processing, featuring a professional in protective clothing meticulously monitoring a stainless steel bioreactor, which is integral to downstream processing and formulation in the chemical industry, within a cleanroom environment.
Downstream Process & Formulation Chemicals

Downstream and formulation chemicals ensure the yield and safety of your drug product throughout the downstream process. Supporting high-risk applications, our chemicals are multi-compendial and manufactured according to GMP guidelines.

View Products
Upstream Process Chemicals
Upstream Process Chemicals

Upstream process chemicals ensure superior performance of your cell culture process driving cell viability, productivity and critical quality attributes of the drug product.

View Products
High quality raw materials supplied globally, in volumes from 1L bottles to 18.000L in tank containers
Cleaning in Place

Our tailor-made, top-quality Cleaning in Place (CIP) solutions help you save time, money, and effort. Instead of preparing your own solutions, simply order the volumes and concentrations you require from our GMP process solutions plant – then integrate them into your own processes. 

View Products

Shop Products

salts (44)

stabilizers (28)

buffers (24)

acids (20)

solvents (20)

coatings (14)

cell culture | mammalian (66)

cell culture | plant (12)

API processing | nano-milling (9)

API processing | polymorph screening (8)

API processing | cocrystal formation (7)

API processing | salt formation (7)

solid (89)

liquid (67)

powder (60)

crystalline (18)

crystalline powder (14)

buffered aqueous glycerol solution (10)
Sort by Relevance
Showing 1-20 of 299
Change View
Showing 1-20 of 299
Benzonase<SUP>®</SUP> Nuclease
E1014

Benzonase® Nuclease

≥250 units/μL, ≥90% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution

Trypsin-EDTA solution
T4049

Trypsin-EDTA solution

0.25%, sterile-filtered, BioReagent, suitable for cell culture, 2.5 g porcine trypsin and 0.2 g EDTA, 4Na per liter of Hanks′ Balanced Salt Solution with phenol red

Water
W3500

Water

sterile-filtered, BioReagent, suitable for cell culture

Sodium hypochlorite solution
425044

Sodium hypochlorite solution

reagent grade, available chlorine 10-15 %

Ethanol
1.00986

Ethanol

absolute, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

Tris(hydroxymethyl)aminomethane
1.08386

Tris(hydroxymethyl)aminomethane

(Trometamol), EMPROVE® EXPERT, Ph. Eur., BP, ChP, JPC, USP

Benzonase<SUP>®</SUP> Nuclease, Purity > 99%
70664

Benzonase® Nuclease

Purity > 99%, Effective viscosity reduction and removal of nucleic acids from protein solutions

Sodium hydroxide solution
S2770

Sodium hydroxide solution

1.0 N, BioReagent, suitable for cell culture

Sodium chloride
1.16224

Sodium chloride

EMPROVE® EXPERT, Ph. Eur., BP, JP, USP

L-Glutamine Solution 200 mM
59202C

L-Glutamine Solution 200 mM

29.23 mg/mL in saline, solution, suitable for cell culture

Sodium hydroxide pellets
1.06482

Sodium hydroxide

pellets, EMPROVE® ESSENTIAL, Ph. Eur., BP, FCC, JP, NF, E 524

Ethanol
1.00971

Ethanol

96%, EMPROVE® EXPERT, Ph. Eur., BP, ChP

Hydrochloric acid
1.00314

Hydrochloric acid

37%, Emprove® ESSENTIAL, Ph. Eur., BP, JP, NF, fuming

Sodium chloride
1.06400

Sodium chloride

EMPROVE® ESSENTIAL, Ph. Eur., BP, USP

Benzonase<SUP>®</SUP> Nuclease, ultrapure
E8263

Benzonase® Nuclease, ultrapure

≥250 units/μL, ≥99% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution, ultrapure grade

Benzonase<SUP>®</SUP> Nuclease, Purity > 90%
70746

Benzonase® Nuclease

Purity > 90%

Glycerol
1.37028

Glycerol

anhydrous (vegetable), EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP, ACS

TWEEN<SUP>®</SUP> 80 (Polysorbate)
8.17061

TWEEN® 80 (Polysorbate)

EMPROVE® ESSENTIAL, Ph. Eur., JP, NF

Benzyl alcohol
1.00987

Benzyl alcohol

EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, NF

Sucrose
1.00892

Sucrose

EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, NF


Sign In To Continue

To continue reading please sign in or create an account.

Don't Have An Account?