SMC® High Sensitivity Immunoassay Kits
SMC® technology enables high sensitivity measurement of biomarkers at femtogram levels, providing insight for early biology to clinical progression through the differentiation of healthy and disease states. This technology, combined with the FemtoQuest™ system or SMCxPRO® instrument and suite of immunoassay kits, provides researchers with the critical tools needed to accelerate their research.
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Products
SMC® Assay Buffer Optimization Kit
SMC® Bead-Based Assay Development Kit (4 Plates)
SMC® Human IL-6 High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human IL-6 in human serum and plasma
SMC® Human IFN-α2 High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human IFNα2 in human serum and plasma
SMC® Human IL-1β High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human IL-1β in human serum and plasma
SMC® Human pTau217 High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human pTau217 in human serum, plasma, and cerebrospinal fluid (CSF)
SMC® Human IL-17F High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human IL-17F in human serum and plasma
SMC® Human PD-1 High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human PD-1 in human serum and plasma
SMC® Human pTau231 High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human pTau231 in human serum, plasma, and cerebrospinal fluid (CSF)
SMC® Human IFNλ1 High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human IFNλ1 (IL-29) in human serum and plasma
SMC® Mouse TNF-α Discovery Immunoassay Kit
Used for ultrasensitive quantification of Mouse TNFα in mouse serum and plasma
SMC® Mouse IL-10 Discovery Immunoassay Kit
Used for ultrasensitive quantification of Mouse IL-10 in mouse serum and plasma.
SMC® Human IL-22 Binding Protein High Sensitivity Immunoassay Kit
SMC® advanced ultrasensitive immunoassay technology
SMC® Human IgE High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human IgE in human serum and plasma
SMC® Mouse IL-4 Discovery Immunoassay Kit
SMC® Mouse IL-17A Discovery Immunoassay Kit
SMC® Human CTLA-4 High Sensitivity Immunoassay Kit
SMC® advanced ultrasensitive immunoassay technology
Digital Counting Improves Sensitivity and Dynamic Range
Providing maximum immunoassay performance while following a workflow similar to traditional ELISA technology, SMC® technology combines a unique assay elution step and robust digital counting to achieve improved signal-to-noise ratios over traditional immunoassay technologies. The SMC® technology thus provides enhanced quantification at both low and high levels of expression on one complete system. The FemtoQuest™ system and SMCxPRO® instrument capture the sum of all digital events counted above the background threshold. The digital event algorithm of the FemtoQuest™ system and SMCxPRO® instrument computes digital events across a spectrum of time series for a single standard. The digital counting of molecules thus improves the assay sensitivity and extends the assay dynamic range beyond what can be achieved with traditional methods.
Verification Criteria for SMC® Immunoassays
A comprehensive set of criteria evaluating ultimate performance are used to qualify verified SMC® immunoassays, including:
- Lower limit of quantification
- Inter- and intra-assay precision
- Spike recovery
- Dilutional linearity and parallelism
SMC® Research Areas
Browse all the ways researchers are using SMC® technology including drug development, neuroscience, cardiotoxicity, immunology research, and more.
Why Choose SMC® Technology?
See why choosing ultrasensitive SMC® technology can help you take a deeper look at your research to discover even more.
SMC® Instrument Platforms
The FemtoQuest™ system, with SMC® assays, enables the measurement of previously undetectable biomarkers. Learn more about our ultrasensitive platforms.
Other SMC® Instrumentation
View info on ancillary kits and equipment for SMC® assays that help optimize your workflows.
Custom Assay Services
Explore more about our Custom Assay Development & Innovation (CADI) services and request more info.
Tips and Support for SMC® Products
Get tips and tricks for running SMC® assays straight from the experts.
Subscribe to Our Newsletter
Stay up to date on the latest immunoassay research trends and our newest product offerings by subscribing to our Analyte Update newsletter or explore our current immunoassay offerings in the Analyte Quarterly.
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