Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are fluoro-compounds used in the manufacturing of several types of food packaging. The add a moisture or oil barrier characteristic to paper-type packaging, including microwave popcorn bags, fast food wrappers, candy wrappers, and pizza box liners. These compounds migrate into foods, and once ingested, increase the risk of kidney disease and other ailments. Solvent extraction, SPE cleanup, and HPLC analysis are the predominant techniques used for these analytes.