Proteomix® Ion-Exchange Phases

High Resolution and High Capacity

Based on non-porous particles, the Proteomix ion-exchange column line from Sepax Technologies was designed to achieve high recovery of peptides, proteins, oligonucleotides, polysaccharides, cell lysates, nanoparticles and nanotubes when analyzed under HPLC or uHPLC conditions. Proteomix columns are packed with spherical, non-porous, poly(styrene divinylbenzene) (PS/DVB) particles that are encapsulated with a hydrophilic, neutral polymer layer to eliminate non-specific binding. Using proprietary coupling chemistry, weak (WAX and WCX) and strong (SAX and SCX) anion and cation exchange functional groups are attached to the hydrophilic bonded phase to obtain a high capacity ion-exchange layer. Proteomix columns are available packed with 1.7, 3, 5 or 10 μm particles that can withstand pressures varying from 4,000 psi (10 μm) up to 10,000 psi (1.7 μm). Non-porous Proteomix ion-exchange columns are unique as they combine increased ion exchange capacity with high efficiency, recovery and throughput.