TOYOPEARL® Bulk Chromatography Media

Tosoh Bioscience offers a comprehensive line of process media for isolation or proteins and nucleic acids in research applications and for large scale purification of biotherapeutics. The process media product line consists of TOYOPEARL® resins for the capture and intermediate purification steps, and TSKgel® resins for the more efficient polishing step. Particle sizes in the TOYOPEARL offering vary from a low of 45 micron to a high of 200 micron, while the average particle sizes of TSKgel resins are 20 and 30 micron respectively. TOYOPEARL resins are available for affinity, ion exchange, hydrophobic interaction, mixed mode and size exclusion chromatography, while high efficiency TSKgel resins are available for anion exchange, cation exchange and hydrophobic interaction chromatography.
Besides their popularity in laboratory-scale product isolation in academic and industrial research laboratories, large columns packed with TOYOPEARL and TSKgel resins can be found anywhere biotherapeutic medicines are manufactured.
Sigma-Aldrich offers TOYOPEARL and TSKgel resins in packaging sizes up to and including 1 L volume.

Affinity

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808002 TOYOPEARL® AF-Amino-650M Bulk Media phase amine-activated, bottle of 25 mL, 65 μm particle size
818074 TOYOPEARL® AF-Amino-650M Bulk Media phase amine-activated, bottle of 1 L, 65 μm particle size
819690 TOYOPEARL® AF-Blue HC-650M Bulk Media phase Cibacron Blue 3GA, 65 μm particle size, bottle of 1 L
818827 TOYOPEARL® AF-Carboxy-650M Bulk Media phase carboxylic acid, bottle of 1 L, 65 μm particle size
814907 TOYOPEARL® AF-Chelate-650M Bulk Media phase IDA, iminodiacetic acid, bottle of 1 L, 65 μm particle size
814475 TOYOPEARL® AF-Chelate-650M Bulk Media phase IDA, iminodiacetic acid, bottle of 25 mL, 65 μm particle size
808000 TOYOPEARL® AF-Epoxy-650M Bulk Media phase expoxy-activated, bottle of 10 g, 65 μm particle size
843402 TOYOPEARL® AF-Epoxy-650M Bulk Media phase iminodiacetic acid, 65 μm particle size, bottle of 5 g
808038 TOYOPEARL® AF-Epoxy-650M Bulk Media phase iminodiacetic acid, bottle of 100 g, 65 μm particle size
843400 TOYOPEARL® AFFIPAK ACT Sampler (AF-Epoxy, Tresyl-650M) phase AF-Epoxy, Tresyl-650M, bottle of 2 × 5 g, 65 μm particle size
817396 TOYOPEARL® AF-Formyl-650M Bulk Media phase aldehyde, bottle of 1 L, 65 μm particle size
808004 TOYOPEARL® AF-Formyl-650M Bulk Media phase aldehyde, bottle of 25 mL, 65 μm particle size
808651 TOYOPEARL® AF-Red-650M bottle of 25 mL, 65 μm particle size
842102 TOYOPEARL® AF-Red-650ML Bulk Media phase Procion Red HE-3B, 65 μm particle size, bottle of 1 L
822806 TOYOPEARL® AF-rProtein A-650F Bulk Media phase rProtein A, bottle of 1 L, 45 μm particle size
823425 TOYOPEARL® AF-rProtein A HC-650F Bulk Media phase rProtein A, bottle of 10 mL, 45 μm particle size
823426 TOYOPEARL® AF-rProtein A HC-650F Bulk Media phase rProtein A, bottle of 25 mL, 45 μm particle size
823427 TOYOPEARL® AF-rProtein A HC-650F Bulk Media phase rProtein A, bottle of 100 mL, 45 μm particle size
823428 TOYOPEARL® AF-rProtein A HC-650F Bulk Media phase rProtein A, bottle of 1 L, 45 μm particle size
843210 TOYOPEARL® AIEXPAK Bulk Media Sampler phase mixed, pkg of 3 × 25 mL, 65, 75, and 100 μm particle size

Anion Exchange

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821987 TOYOPEARL® Q-600C AR Bulk Media phase ammonium ion, quaternary, bottle of 1 L, 100 μm particle size
821985 TOYOPEARL® Q-600C AR Bulk Media phase ammonium ion, quaternary, bottle of 100 mL, 100 μm particle size
821986 TOYOPEARL® Q-600C AR Bulk Media phase ammonium ion, quaternary, bottle of 250 mL, 100 μm particle size
807472 TOYOPEARL® DEAE-650S Bulk Media phase DEAE (diethylaminoethyl), bottle of 250 mL, 35 μm particle size
814692 TOYOPEARL® DEAE-650S Bulk Media phase DEAE (diethylaminoethyl), bottle of 1 L, 35 μm particle size
819804 TOYOPEARL® DEAE-650S Bulk Media phase DEAE (diethylaminoethyl), bottle of 25 mL, 35 μm particle size
807988 TOYOPEARL® DEAE-650C Bulk Media phase DEAE (diethylaminoethyl), bottle of 250 mL, 100 μm particle size
814694 TOYOPEARL® DEAE-650C Bulk Media phase DEAE (diethylaminoethyl), bottle of 1 L, 100 μm particle size
807473 TOYOPEARL® DEAE-650M Bulk Media phase DEAE (diethylaminoethyl), bottle of 250 mL, 65 μm particle size
814693 TOYOPEARL® DEAE-650M Bulk Media phase DEAE (diethylaminoethyl), bottle of 1 L, 65 μm particle size
843201 TOYOPEARL® DEAE-650M Bulk Media phase DEAE (diethylaminoethyl), bottle of 100 mL, 65 μm particle size
822881 TOYOPEARL GigaCap® Q-650S Bulk Media phase ammonium ion, quaternary, bottle of 25 mL, 35 μm particle size
822882 TOYOPEARL GigaCap® Q-650S Bulk Media phase ammonium ion, quaternary, bottle of 250 mL, 35 μm particle size
821856 TOYOPEARL GigaCap® Q-650M Bulk Media phase ammonium ion, quaternary, bottle of 1 L, 75 μm particle size
821854 TOYOPEARL GigaCap® Q-650M Bulk Media phase ammonium ion, quaternary, bottle of 100 mL, 75 μm particle size
821855 TOYOPEARL GigaCap® Q-650M Bulk Media phase ammonium ion, quaternary, bottle of 250 mL, 75 μm particle size
822865 TOYOPEARL GigaCap® DEAE-650M Bulk Media phase DEAE (diethylaminoethyl), bottle of 100 mL, 75 μm particle size
822866 TOYOPEARL GigaCap® DEAE-650M Bulk Media phase DEAE (diethylaminoethyl), bottle of 250 mL, 75 μm particle size
819817 TOYOPEARL® IEXPAK HP Bulk Media Sampler phase various, pkg of 4 × 25 mL, 35 μm particle size
814704 TOYOPEARL® QAE-550C Bulk Media phase ammonium ion, quaternary, bottle of 1 L, 100 μm particle size
814026 TOYOPEARL® QAE-550C Bulk Media phase ammonium ion, quaternary, bottle of 250 mL, 100 μm particle size
843271 TOYOPEARL® QAE-550C Bulk Media phase ammonium ion, quaternary, bottle of 100 mL, 100 μm particle size
819823 TOYOPEARL® SuperQ-650S Bulk Media phase ammonium ion, quaternary, bottle of 25 mL, 35 μm particle size
817223 TOYOPEARL® SuperQ-650S Bulk Media phase ammonium ion, quaternary, bottle of 250 mL, 35 μm particle size
817224 TOYOPEARL® SuperQ-650S Bulk Media phase ammonium ion, quaternary, bottle of 1 L, 35 μm particle size
843275 TOYOPEARL® SuperQ-650C Bulk Media phase ammonium ion, quaternary, bottle of 100 mL, 100 μm particle size
817231 TOYOPEARL® SuperQ-650C Bulk Media phase ammonium ion, quaternary, bottle of 250 mL, 100 μm particle size
817232 TOYOPEARL® SuperQ-650C Bulk Media phase ammonium ion, quaternary, bottle of 1 L, 100 μm particle size
817228 TOYOPEARL® SuperQ-650M Bulk Media phase ammonium ion, quaternary, bottle of 1 L, 65 μm particle size
843205 TOYOPEARL® SuperQ-650M Bulk Media phase ammonium ion, quaternary, bottle of 100 mL, 65 μm particle size
817227 TOYOPEARL® SuperQ-650M Bulk Media phase ammonium ion, quaternary, bottle of 250 mL, 65 μm particle size

Cation Exchange

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821833 TOYOPEARL GigaCap® S-650M Bulk Media phase sulphonyl, bottle of 100 mL, 75 μm particle size
843220 TOYOPEARL® CIEXPAK Bulk Media Sampler pkg of 3 × 25 mL, phase mixed, 75, 100 μm particle size
807474 TOYOPEARL® CM-650S Bulk Media phase carboxymethyl, bottle of 250 mL, 35 μm particle size
807991 TOYOPEARL® CM-650C Bulk Media phase carboxymethyl, bottle of 250 mL, 100 μm particle size
807475 TOYOPEARL® CM-650M Bulk Media phase carboxymethyl, bottle of 250 mL, 65 μm particle size
822875 TOYOPEARL GigaCap® S-650S Bulk Media phase sulphonyl, bottle of 25 mL, 35 μm particle size
822876 TOYOPEARL GigaCap® S-650S Bulk Media phase sulphonyl, bottle of 250 mL, 35 μm particle size
821834 TOYOPEARL GigaCap® S-650M Bulk Media phase sulphonyl, bottle of 250 mL, 75 μm particle size
819817 TOYOPEARL® IEXPAK HP Bulk Media Sampler phase various, pkg of 4 × 25 mL, 35 μm particle size
821806 TOYOPEARL MegaCap® II SP-550EC Bulk Media phase sulphonyl, bottle of 1 L, 200 μm particle size
821804 TOYOPEARL MegaCap® II SP-550EC Bulk Media phase sulphonyl, bottle of 100 mL, 200 μm particle size
821805 TOYOPEARL MegaCap® II SP-550EC Bulk Media phase sulphonyl, bottle of 250 mL, 200 μm particle size
814705 TOYOPEARL® SP-550C Bulk Media phase sulfopropyl, bottle of 1 L, 100 μm particle size
843272 TOYOPEARL® SP-550C Bulk Media phase sulfopropyl, bottle of 100 mL, 100 μm particle size
819822 TOYOPEARL® SP-650S Bulk Media phase sulphonyl, bottle of 25 mL, 35 μm particle size
814698 TOYOPEARL® SP-650S Bulk Media phase sulphonyl, bottle of 1 L, 35 μm particle size
808437 TOYOPEARL® SP-650S Bulk Media phase sulphonyl, bottle of 250 mL, 35 μm particle size
814700 TOYOPEARL® SP-650C Bulk Media phase sulphonyl, bottle of 1 L, 100 μm particle size
814699 TOYOPEARL® SP-650M Bulk Media phase sulphonyl, bottle of 1 L, 65 μm particle size
843202 TOYOPEARL® SP-650M Bulk Media phase sulphonyl, bottle of 100 mL, 65 μm particle size

Hydrophobic Interaction

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821450 TOYOPEARL® Butyl-600M Bulk Media bottle of 1 L, 65 μm particle size
821449 TOYOPEARL® Butyl-600M Bulk Media bottle of 100 mL, 65 μm particle size
821448 TOYOPEARL® Butyl-600M Bulk Media bottle of 25 mL, 65 μm particle size
807476 TOYOPEARL® Butyl-650S Bulk Media phase C4 (butyl), bottle of 100 mL, 35 μm particle size
814701 TOYOPEARL® Butyl-650S Bulk Media phase C4 (butyl), bottle of 1 L, 35 μm particle size
843153 TOYOPEARL® Butyl-650S Bulk Media phase C4 (butyl), bottle of 25 mL, 35 μm particle size
807478 TOYOPEARL® Butyl-650C Bulk Media phase C4 (butyl), bottle of 100 mL, 100 μm
843127 TOYOPEARL® Butyl-650C Bulk Media phase C4 (butyl), bottle of 25 mL, 100 μm particle size
814703 TOYOPEARL® Butyl-650C Bulk Media phase C4 (butyl), bottle of 1 L, 100 μm particle size
807477 TOYOPEARL® Butyl-650M Bulk Media matrix polymer (65 μm), bottle of 100 mL, 65 μm
814702 TOYOPEARL® Butyl-650M Bulk Media phase C4 (butyl), bottle of 1 L, 65 μm particle size
816174 TOYOPEARL® Ether-650S Bulk Media phase ether, bottle of 1 L, 35 μm particle size
816172 TOYOPEARL® Ether-650S Bulk Media phase ether, bottle of 100 mL, 35 μm particle size
843151 TOYOPEARL® Ether-650S Bulk Media phase ether, bottle of 25 mL, 35 μm particle size
819805 TOYOPEARL® Ether-650M Bulk Media phase ether, bottle of 25 mL, 65 μm particle size
816173 TOYOPEARL® Ether-650M Bulk Media matrix polymer (65 μm), bottle of 100 mL, 100 μm
816175 TOYOPEARL® Ether-650M Bulk Media phase ether, bottle of 1 L, 65 μm particle size
819027 TOYOPEARL® Hexyl-650C Bulk Media phase C6 (hexyl), bottle of 1 L, 100 μm particle size
819026 TOYOPEARL® Hexyl-650C Bulk Media phase C6 (hexyl), bottle of 100 mL, 100 μm particle size
844465 TOYOPEARL® Hexyl-650C Bulk Media phase C6 (hexyl), bottle of 25 mL, 100 μm particle size
819806 TOYOPEARL® HICPAK Bulk Media Sampler phase Ether, Phenyl, Butyl-650M, pkg of 3 × 25 mL, 65 μm particle size
821889 TOYOPEARL® Phenyl-600 HIC Bulk Media phase phenyl, bottle of 1 L, 65 μm particle size
821888 TOYOPEARL® Phenyl-600 HIC Bulk Media phase phenyl, bottle of 100 mL, 65 μm particle size
821887 TOYOPEARL® Phenyl-600 HIC Bulk Media phase phenyl, bottle of 25 mL, 65 μm particle size
814477 TOYOPEARL® Phenyl-650S Bulk Media phase phenyl, bottle of 100 mL, 35 μm particle size
814784 TOYOPEARL® Phenyl-650S Bulk Media phase phenyl, bottle of 1 L, 35 μm particle size
843152 TOYOPEARL® Phenyl-650S Bulk Media phase phenyl, bottle of 25 mL, 35 μm particle size
843126 TOYOPEARL® Phenyl-650C Bulk Media phase phenyl, bottle of 25 mL, 100 μm particle size
814785 TOYOPEARL® Phenyl-650C Bulk Media bottle of 1 L, phase phenyl, 100 μm particle size
814479 TOYOPEARL® Phenyl-650C Bulk Media phase phenyl, bottle of 100 mL, 100 μm particle size
819818 TOYOPEARL® Phenyl-650M Bulk Media phase phenyl, bottle of 25 mL, 65 μm particle size
814783 TOYOPEARL® Phenyl-650M Bulk Media phase phenyl, bottle of 1 L, 65 μm particle size
814478 TOYOPEARL® Phenyl-650M Bulk Media matrix polymer (65 μm), bottle of 100 mL, 65 μm
821303 TOYOPEARL® PPG-600M Bulk Media phase polypropylene glycol, bottle of 1 L, 65 μm particle size
821302 TOYOPEARL® PPG-600M Bulk Media phase polypropylene glycol, bottle of 100 mL, 65 μm particle size
821301 TOYOPEARL® PPG-600M Bulk Media phase polypropylene glycol, bottle of 25 mL, 65 μm particle size
819957 TOYOPEARL® SuperButyl-550C Bulk Media phase C4 (butyl), bottle of 1 L, 100 μm particle size
819956 TOYOPEARL® SuperButyl-550C Bulk Media phase C4 (butyl), bottle of 100 mL, 100 μm particle size
819955 TOYOPEARL® SuperButyl-550C Bulk Media phase C4 (butyl), bottle of 25 mL, 100 μm particle size

Mixed Mode

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822819 TOYOPEARL® MX-Trp-650M Bulk Media phase tryptophan, bottle of 1 L, 75 μm particle size
822818 TOYOPEARL® MX-Trp-650M Bulk Media phase tryptophan, bottle of 100 mL, 75 μm particle size
822817 TOYOPEARL® MX-Trp-650M Bulk Media phase tryptophan, bottle of 25 mL, 75 μm particle size

Size Exclusion

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819819 TOYOPEARL® HMW Size Exclusion Sampler, (HW-55, 65, 75F), 45 μm particles HMW, phase hydroxylated methacrylic polymer, bottle of 3 × 150 mL, particle size 45 μm
819820 TOYOPEARL® HP Size Exclusion Sampler, (HW-40, 50, 55, 65S), 30 μm particles HP, phase hydroxylated methacrylic polymer, bottle of 4 × 150 mL, 30 μm particle size
814681 TOYOPEARL® HW-40S Bulk Media phase hydroxylated methacrylate, bottle of 1 L, 30 μm particle size
819809 TOYOPEARL® HW-40S Bulk Media phase hydroxylated methacrylic polymer, bottle of 150 mL, 30 μm particle size
807447 TOYOPEARL® HW-40S Bulk Media phase hydroxylated methacrylate, bottle of 500 mL, 30 μm particle size
807451 TOYOPEARL® HW-40S Bulk Media phase hydroxylated methacrylate, bottle of 250 mL, 30 μm particle size
807449 TOYOPEARL® HW-40C Bulk Media phase hydroxylated methacrylate, bottle of 500 mL, 75 μm particle size
814683 TOYOPEARL® HW-40C Bulk Media phase hydroxylated methacrylate, bottle of 1 L, 75 μm particle size
819807 TOYOPEARL® HW-40C Bulk Media phase hydroxylated methacrylate, bottle of 150 mL, 75 μm particle size
814682 TOYOPEARL® HW-40F Bulk Media phase hydroxylated methacrylate, bottle of 1 L, 45 μm particle size
807448 TOYOPEARL® HW-40F Bulk Media phase hydroxylated methacrylate, bottle of 500 mL, 30-60 μm
819811 TOYOPEARL® HW-50S Bulk Media phase hydroxylated methacrylate, bottle of 150 mL, 30 μm particle size
807452 TOYOPEARL® HW-50S Bulk Media phase hydroxylated methacrylate, bottle of 500 mL, 30 μm particle size
814684 TOYOPEARL® HW-50S Bulk Media phase hydroxylated methacrylate, bottle of 1 L, 35 μm particle size
807455 TOYOPEARL® HW-50S Bulk Media matrix hydroxylated methacrylate, bottle of 250 mL, 20-40 μm
819810 TOYOPEARL® HW-50F Bulk Media phase hydroxylated methacrylate, bottle of 150 mL, 45 μm particle size
814685 TOYOPEARL® HW-50F Bulk Media phase hydroxylated methacrylate, bottle of 1 L, 45 μm particle size
807453 TOYOPEARL® HW-50F Bulk Media matrix hydroxylated methacrylate, bottle of 500 mL, 30-60 μm
819813 TOYOPEARL® HW-55S Bulk Media phase hydroxylated methacrylic polymer, bottle of 150 mL, 30 μm particle size
807456 TOYOPEARL® HW-55S Bulk Media phase hydroxylated methacrylic polymer, bottle of 500 mL, 30 μm particle size
814686 TOYOPEARL® HW-55S Bulk Media phase hydroxylated methacrylic polymer, bottle of 1 L, 30 μm particle size
807459 TOYOPEARL® HW-55S Bulk Media phase hydroxylated methacrylic polymer, bottle of 250 mL, 20-40 μm
819812 TOYOPEARL® HW-55F Bulk Media phase hydroxylated methacrylate, bottle of 150 mL, 45 μm particle size
814687 TOYOPEARL® HW-55F Bulk Media phase hydroxylated methacrylate, bottle of 1 L, 45 μm particle size
807457 TOYOPEARL® HW-55F Bulk Media phase hydroxylated methacrylate, bottle of 500 mL, 45 μm particle size
819815 TOYOPEARL® HW-65S Bulk Media phase hydroxylated methacrylic polymer, bottle of 150 mL, 30 μm particle size
814688 TOYOPEARL® HW-65S Bulk Media phase hydroxylated methacrylic polymer, bottle of 1 L, 30 μm particle size
807467 TOYOPEARL® HW-65S Bulk Media phase hydroxylated methacrylic polymer, bottle of 250 mL, 20-40 μm
821481 TOYOPEARL® HW-65C Bulk Media phase hydroxylated methacrylic polymer, bottle of 150 mL, 75 μm particle size
814690 TOYOPEARL® HW-65C Bulk Media phase hydroxylated methacrylic polymer, bottle of 1 L, 75 μm particle size
807466 TOYOPEARL® HW-65C Bulk Media phase hydroxylated methacrylic polymer, bottle of 500 mL, 75 μm particle size
819814 TOYOPEARL® HW-65F Bulk Media phase hydroxylated methacrylate, bottle of 150 mL, 45 μm particle size
814689 TOYOPEARL® HW-65F Bulk Media phase hydroxylated methacrylate, bottle of 1 L, 45 μm particle size
807465 TOYOPEARL® HW-65F Bulk Media phase hydroxylated methacrylate, bottle of 500 mL, 30-60 μm particle size
807468 TOYOPEARL® HW-75S Bulk Media phase hydroxylated methacrylic polymer, bottle of 500 mL, 30 μm particle size
807471 TOYOPEARL® HW-75S Bulk Media phase hydroxylated methacrylic polymer, bottle of 250 mL, 30 μm particle size
814691 TOYOPEARL® HW-75F Bulk Media phase hydroxylated methacrylate, bottle of 1 L, 45 μm particle size
819816 TOYOPEARL® HW-75F Bulk Media phase hydroxylated methacrylate, bottle of 150 mL, 45 μm particle size
819808 TOYOPEARL® HW-40F Bulk Media phase hydroxylated methacrylate, bottle of 150 mL, 45 μm particle size
807450 TOYOPEARL® HW-40EC Bulk Media phase hydroxylated methacrylic polymer, bottle of 500 mL, 200 μm particle size
819821 TOYOPEARL® LMW Size Exclusion Sampler, (HW-40, 50, 55F), 45 μm particles LMW, phase hydroxylated methacrylic polymer, bottle of 3 × 150 mL, 45 μm particle size
807464 TOYOPEARL HW-65S Bulk Media phase hydroxylated methacrylic polymer, bottle of 500 mL, 30 μm particle size