Opiates

Opiates are naturally occurring alkaloids typically prescribed for the treatment of acute and chronic pain. These drugs have a high addiction potential, are widely available, and potentially lethal when not taken as prescribed. The use of opioids such as hydrocodone, oxycodone and others has been increasing since the late-90s due to over-prescription and their high potential for dependence. Until today, the worldwide use and misuse of opiates continued to increase dramatically and according to the Center for Disease Control and Prevention (CDC) opioid misuse and the emergence of highly potent fentanyl analogues is causing the highest overdose death rates ever recorded in the United States. Stricter regulations, particularly in the US, have increased the need for opioid testing. Opiate analysis has historically been performed using GC/MS, where a typical workflow includes acid or enzyme hydrolysis of opiate glucuronides and derivatization prior to analysis. Today clinical and forensic toxicology labs have been adopting LC-MS/MS over GC/MS for the analysis of opiates due to the technique′s increased sensitivity, higher specificity, and reduced time spent on sample preparation.

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A-053 6-Acetylcodeine solution 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
A-026 6-Acetylmorphine-d6 solution 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
A-027 6-Acetylmorphine-d6 solution 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
A-003 6-Acetylmorphine, 100 μg/mL solution 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
A-009 6-Acetylmorphine, 1.0 mg/mL solution 1 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
A-006 6-Acetylmorphine-d3 solution 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
A-010 6-Acetylmorphine-d3 solution 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
B7536 Buprenorphine hydrochloride solution analytical standard, for drug analysis
B-044 Buprenorphine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
B-902 Buprenorphine solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
B-901 Buprenorphine-D4 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
B-908 Buprenorphine-D4 solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
B-035 Buprenorphine glucuronide solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
B-037 Butorphanol tartrate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
C5901 Codeine monohydrate analytical standard
C-006 Codeine solution 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
C-015 Codeine solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
C3539 Codeine-d3 hydrochloride dihydrate analytical standard, 98 atom % D
C-005 Codeine-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
C-007 Codeine-D3 solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
C-040 Codeine-D6 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
C-041 Codeine-D6 solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
C-087 Codeine-6-β-D-glucuronide solution 100 μg/mL in methanol: water (2:8), ampule of 1 mL, certified reference material, Cerilliant®
C-138 Codeine-6-ß-D-glucuronide-D3 solution 100 μg/mL in methanol: water (2:8), ampule of 1 mL, certified reference material, Cerilliant®
D-103 Desomorphine-D3 solution 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
D-013 Dextromethorphan solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
D-071 Dextromethorphan-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
D-034 Dextrorphan tartrate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-041 Dextrorphan-d3 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
D-019 Dihydrocodeine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-021 Dihydrocodeine-D6 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-087 Dihydrocodeine-D6 hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-033 Dihydromorphine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
E-052 Ethylmorphine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H159 Heroin analytical standard, ≥98% (HPLC)
H5144 Heroin hydrochloride solution 100 μg/mL in methanol, analytical standard, for drug analysis
H-038 Heroin solution 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
H-036 Heroin-D9 solution 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
H-037 Heroin-D9 solution 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
H-003   Hydrocodone solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-005 Hydrocodone-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-008 Hydrocodone-D3 solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-048 Hydrocodone-D6 solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-047 Hydrocodone-D6 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-004 Hydromorphone solution 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-006 Hydromorphone-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-010 Hydromorphone-D3 solution 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-050 Hydromorphone-D6 solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-049 Hydromorphone-D6 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-051 Hydromorphone-3-β-D-glucuronide 100 μg/mL in methanol: water (1:1), ampule of 1 mL, certified reference material, Cerilliant®
IMPM-005-05 10-Hydroxymorphine solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
IMPN-007-02 10-Hydroxynaltrexone solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-098 6α/β-Hydroxyoxymorphone-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
IMPN-007-03 10-Ketonaltrexone solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
L-010 Levomethorphan vial of 10 mg, certified reference material, Cerilliant®
M187 (+)-3-Methoxymorphinan hydrochloride analytical standard, for drug analysis
M-005 Morphine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
M-030 Morphine solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
M9524 Morphine sulfate salt solution 1.0 mg/mL in methanol, drug standard
M-006 Morphine-D3 solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
M-003 Morphine-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
M3402 Morphine-d3 hydrochloride trihydrate analytical standard
M-085 Morphine-D6 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
M-086 Morphine-D6 solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
M-031 Morphine-3-β-D-glucuronide solution 1 mg/mL in methanol with 0.05% NaOH, ampule of 1 mL, certified reference material, Cerilliant®
M-018 Morphine-3-β-D-glucuronide solution 100 μg/mL in methanol: water (1:1), ampule of 1 mL, certified reference material, Cerilliant®
M-017 Morphine-D3-3-β-D-glucuronide solution 100 μg/mL in methanol with 0.05% NaOH, ampule of 1 mL, certified reference material, Cerilliant®
M-046 Morphine-6-β-D-glucuronide solution 1.0 mg/mL in methanol: water (2:8), ampule of 1 mL, certified reference material, Cerilliant®
M-096 Morphine-6-β-D-glucuronide solution 100 μg/mL in methanol: water (1:1), ampule of 1 mL, certified reference material, Cerilliant®
M-120 Morphine-6-β-D-glucuronide-D3 solution 100 μg/mL in methanol: water (1:1), ampule of 1 mL, certified reference material, Cerilliant®
IMPM-005-01 Morphine N-oxide solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-051 Nalbuphine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-056   Nalbuphine-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-924 Nalorphine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-103 6α-Naloxol solution 1.0 mg/mL in methanol, certified reference material, Cerilliant®
N-004 Naloxone solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-063 Naloxone-D5 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-115 Naloxone-D5 solution 1.0 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
N-099   Naloxone-3ß-D-glucuronide solution 1.0 mg/mL in methanol: water (9:1), ampule of 1 mL, certified reference material, Cerilliant®
IMPN-007-04 Naloxone N-oxide solution 100 μg/mL in acetonitrile: water (1:1), ampule of 1 mL, certified reference material, Cerilliant®
N-038 6β-Naltrexol solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-081 6β-Naltrexol-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-104 6β-Naltrexol-3-β-D-glucuronide 1.0 mg/mL (20% Water in Acetonitrile), certified reference material, Cerilliant®
N-007 Naltrexone solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-047 Naltrexone-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-106   Naltrexone-3-β-D-glucuronide solution 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
N-108   Naltrexone-D3-3-β-D-glucuronide solution 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
N-912 Norbuprenorphine solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-059 Norbuprenorphine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-920 Norbuprenorphine-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-921 Norbuprenorphine-D3 solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-045 Norbuprenorphine glucuronide solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-097   Norbuprenorphine glucuronide-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-005 Norcodeine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-082 Norcodeine-d3 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-054 Norhydrocodone-d3 hydrochloride 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-143 Norhydrocodone-D3 hydrochloride solution 1 mg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
N-053 Norhydrocodone hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-107   Norhydromorphone hydrochloride solution 1.0 mg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
N-006 Normorphine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-011 Noroxycodone hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-032 Noroxycodone-D3 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-033 Noroxycodone-D3 hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-012 Noroxymorphone hydrochloride solution 1.0 mg/mL in methanol: DMSO (80:20) (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-013 Noroxymorphone hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-111   Noroxymorphone-3-ß-D-glucuronide solution 100 μg/mL in methanol: water (2:8), certified reference material, ampule of 1 mL, Cerilliant®
IMPM-005-06 10-Oxomorphine solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
O-002 Oxycodone solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
O-005 Oxycodone-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
O-006 Oxycodone-D3 solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
O-008 Oxycodone-D6 solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
O-007 Oxycodone-D6 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
O-004 Oxymorphone solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
O-003 Oxymorphone-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
O-019 Oxymorphone-D3 solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
O-030 Oxymorphone-3-β-D-glucuronide solution 100 μg/mL in methanol: water (1:1), ampule of 1 mL, certified reference material, Cerilliant®
O-031 Oxymorphone-D3-3-β-D-glucuronide solution 100 μg/mL in methanol: water (1:1), ampule of 1 mL, certified reference material, Cerilliant®
P-119   Pholcodine solution 1.0 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
S-098 (-)-Scopolamine hydrobromide solution 1.0 mg/mL in acetonitrile: water (9:1) (as free base), certified reference material, ampule of 1 mL, Cerilliant®
S-099 (-)-Scopolamine-D3 hydrochloride solution 100 μg/mL in acetonitrile: water (9:1) (as free base), certified reference material, ampule of 1 mL, Cerilliant®
S-018 Sufentanil-D5 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
S-008 Sufentanil Citrate solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
T-116 Thebaine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®