NSAIDS

Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of pharmaceuticals used in both human and veterinary medicine to treat acute and chronic pain, inflammation, and fever. NSAIDs exert their effects through inhibition of cyclooxygenase (COX), an enzyme that catalyzes the production of prostacyclins or compounds key to the inflammation response. Acute and chronic use of NSAIDs are associated with adverse side effects including gastrointestinal, liver, and renal damage as well as cardiovascular complications. Immunoassays are available for some NSAID medications including acetylsalicylic acid and acetaminophen. For NSAIDs like naproxen, ibuprofen, and indomethacin, immunoassay availability is limited or nonexistent which is why clinical and forensic analysis of these drugs are typically performed using mass spectrometry-based methods. NSAIDs such as ibuprofen have also been detected as adulterants in food and dietary supplements and are analyzed by regulatory agencies and quality control laboratories to ensure product quality and potency.

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H-052 4′-Hydroxydiclofenac solution 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
H-053 4′-Hydroxydiclofenac-13C6 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
I-009 Ibuprofen solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
I-032 Ibuprofen-D3 solution 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
N-042 Naproxen solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®