Antipsychotics

Antipsychotics are a class of drugs used to treat a variety of mental health conditions, including schizophrenia spectrum disorders, bipolar disorder, attention-deficit/hyperactivity disorder (ADHD), opiate and alcohol addiction, sleep disorders, and depression. Antipsychotics have serious adverse effects associated with their use including rapid weight gain, diabetes, cardiovascular disease, and movement impairment. Antipsychotics are separated into two classes - first generation drugs known as typicals and newer second generation drugs called atypicals. Both atypical and typical antipsychotics are routinely analyzed in clinical and forensic applications. For clinical and diagnostic testing, therapeutic drug monitoring (TDM) of antipsychotics may be indicated to assess medication adherence and to ensure dosing remains within the therapeutic range. While antipsychotics have historically been analyzed by GC/MS, many of the newer atypicals such as risperidone are not suitable for GC analysis due to thermal instability. HPLC and LC/MS have supplanted GC/MS for the analysis of antipsychotics in biological matrices, because liquid chromatographic systems do not require volatilization or derivatization of the analyte.

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32090 Acepromazine-(dimethyl-d6) maleate analytical standard
A-119 Aripiprazole solution 1.0 mg/mL (50:50 Methanol/Water with 1% 1N HCl), ampule of 1 mL, certified reference material, Cerilliant®
A-081 Aripiprazole-d8 solution 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
A-101 Asenapine maleate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
A-159 Asenapine-D3 maleate solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
32738 Azaperol VETRANAL®, analytical standard
34223 Azaperone VETRANAL®, analytical standard
32854 Azaperone-d4 VETRANAL®, analytical standard
B-076 Brexpiprazole-D8 solution 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®
B-078   Bromperidol solution 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
C-179   Cariprazine-D8 solution 100 μg/mL (0.1% HCl in Acetonitrile (v/v)), certified reference material, ampule of 1 mL, Cerilliant®
32554 Chlorpromazin-d6 hydrochloride VETRANAL®, analytical standard
31679 Chlorpromazine hydrochloride VETRANAL®, analytical standard
C-904 Chlorpromazine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
C-107 Chlorpromazine-D3 maleate solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
C-059 Clozapine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
C-091 Clozapine-D4 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
C-125   Clozapine N-oxide solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
D-053 Dehydro aripiprazole solution 1.0 mg/mL in methanol with 5% 1 M HCl, ampule of 1 mL, certified reference material, Cerilliant®
D-169   N-Desmethylclozapine-D8 solution 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
D-048 N-Desmethylclozapine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
D-069 Desmethylolanzapine dihydrochloride solution 1.0 mg/mL in acetonitrile: water (1:1) (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-070 N-Desmethylolanzapine-d8 dihydrochloride solution 100 μg/mL in acetonitrile: water (1:1) (as free base), ampule of 1 mL, certified reference material, Cerilliant®
F-903 Fluphenazine dihydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
H-030 Haloperidol solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-002 Haloperidol-D4 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H102 Haloperidol metabolite II analytical standard
H-104   Hydroxy Iloperidone solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-125 5beta/6beta-Hydroxy Lurasidone (Mixture of Diastereomers) solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-081 7-Hydroxyquetiapine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-076 9-Hydroxyrisperidone solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
H-095 9-Hydroxyrisperidone-D4 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
I-011 Iloperidone solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
I-013   Iloperidone-13C,D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
L-052 Loxapine succinate solution 1 mg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
L-030 Lurasidone hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
L-035   Lurasidone-D8 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
M-234 Molindone hydrochloride solution 1 mg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
N-070 Norquetiapine hydrochloride 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-121 Norquetiapine-D8 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
O-024 Olanzapine solution 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
O-035 Olanzapine-d8 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
O-049 OPC-3373 (Aripiprazole Metabolite) solution 1 mg/mL (Acetonitrile:DMSO (9:1)), certified reference material, ampule of 1 mL, Cerilliant®
O-046 OPC-3373-D4 (Aripiprazole Metabolite-D4) solution 100 μg/mL (Acetonitrile:DMSO (9:1)), certified reference material, ampule of 1 mL, Cerilliant®
46674 Promazine hydrochloride VETRANAL®, analytical standard
Q-001 Quetiapine fumarate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
Q-002 Quetiapine-D8 hemifumarate solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
Q-004 Quetiapine carboxylic acid solution 1.0 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®
Q-005 Quetiapine carboxylic acid-D8 solution 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®
R-006 Risperidone solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
R-013 Risperidone-D4 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
34002 (S)-(−)-Sulpiride VETRANAL®, analytical standard
T-905 Thioridazine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
T-135   Thioridazine-D3 hydrochloride solution 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
T-117 Trifluoperazine dihydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
T-118 Trifluoperazine N-ß-D-glucuronide solution 100 μg/mL in methanol: water (1:1), analytical standard, ampule of 1 mL, Cerilliant®
46976 Triflupromazine hydrochloride VETRANAL®, analytical standard
T-128 Triflupromazine hydrochloride solution 1 mg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
32110 Triflupromazine-(dimethyl-d6) hydrochloride VETRANAL®, analytical standard
Z-018 Ziprasidone hydrochloride solution 1.0 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
Z-019 Ziprasidone-D8 hydrochloride solution 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®