Antihistamines

Antihistamines are popular medications used for symptomatic relief of cold and allergy symptoms and as sleeping aids. These drugs can produce intense feelings of sedation, which reportedly can be enhanced by alcohol. Although relatively safe, antihistamine use is implicated in motor vehicle, civil aviation, and boating accidents with deaths resulting from accidental or intentional overdose. Antihistamines function by inhibiting the action of histamine, a compound that regulates immediate hypersensitivity and allergic response. Currently available antihistamines are classified as either first generation H1 receptor agonists or as second generation H2 receptor agonists. These drugs, especially diphenhydramine, chlorpheniramine, and promethazine, are routinely analyzed in forensic laboratories to determine cause of death in cases of suspected suicide or drug-facilitated crime.

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A3766 Antazoline phosphate salt analytical standard, for drug analysis
B-043 Brompheniramine maleate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
C8278 Carbinoxamine maleate salt analytical standard
C-158 Cetirizine dihydrochloride solution 1.0 mg/mL in acetonitrile: water (9:1) (as free base), ampule of 1 mL, certified reference material, Cerilliant®
C1915 Chloropyramine hydrochloride analytical standard, for drug analysis
C-036 Chlorpheniramine maleate salt solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
C-086 Chlorpheniramine-D6 maleate solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-015 Diphenhydramine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-017 Diphenhydramine-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
D-051 Doxylamine-D5 solution 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
D-045 Doxylamine succinate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
F-081 Fexofenadine hydrochloride solution 1 mg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant® New
H-124 Hydroxyzine dihydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
M5279 Mebhydroline 1,5-naphthalenedisulfonate salt analytical standard
442641   Methapyrilene HCl analytical standard
M7780 3-Methylhistamine dihydrochloride analytical standard
62226 2-[(RS)-(4-Methylphenyl)phenylmethoxy]-N,N-dimethylethanamine hydrochloride pharmaceutical impurity standard
O4630 Orphenadrine citrate salt analytical standard
P-045 Pheniramine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
P4545 Pimethixene maleate salt analytical standard
46682 Promethazine hydrochloride VETRANAL, analytical standard
P-111   Promethazine hydrochloride solution 1.0 mg/mL (1% 1 M HCl in Methanol (as free base)), ampule of 1 mL, certified reference material, Cerilliant®
P-112   Promethazine-D3 hydrochloride solution 100 μg/mL (1% 1 M HCl in Methanol (as free base)), ampule of 1 mL, certified reference material, Cerilliant®
T7511 Tripelennamine hydrochloride analytical standard