Antidepressants

Antidepressants are drugs used to treat of major depressive disorder and other conditions, including anxiety disorders, chronic pain conditions (off-label use), and to help manage addictions. Common side-effects of antidepressants include dry mouth, weight gain, dizziness, headaches, and sexual dysfunction. Depression is a psychiatric condition that affects an estimated 350 million people worldwide and can impair an individual′s ability to take care of their everyday responsibilities. Widely used to manage depression and related mood disorders, antidepressants may be grouped into major classes consisting of selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclics (TCAs), monoamine oxidase inhibitors (MAOIs), and tetracyclics. Antidepressants have expanded in use with prescription rates increasing worldwide. Explanations for rising antidepressant use include increased cultural acceptance of antidepressants and extended efficacy of antidepressants for multiple health conditions. Since antidepressants can impair cognitive and psychomotor function and may increase the risk of driving accidents or voluntary intoxication, they are routinely analyzed in forensic analysis or clinical toxicology applications using mass spectrometry methods. In a clinical setting, therapeutic drug monitoring (TDM) of tricyclic antidepressants may be performed to reduce drug-drug interactions, to monitor patient compliance, and to optimize dosing within the drug′s therapeutic range.

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A-923 Amitriptyline hydrochloride solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
A-085 Amitriptyline-d3 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
A-121 Amitriptyline-d3 hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
A115 Amitriptyline metabolite, (±)-E-10-hydroxylated- analytical standard
A-128 Amitriptyline N-ß-D-glucuronide solution 100 μg/mL in acetonitrile: water (1:1), certified reference material, ampule of 1 mL, Cerilliant®
A-123 Amoxapine 1.0 mg/mL in methanol, certified reference material, Cerilliant®
A-158 Amoxapine-D8 solution 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
B-034 Bupropion hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
B-052 (±)-Bupropion-D9 hydrochloride solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
B-054 Buspirone hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
B-055 Buspirone-D8 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
C-095 Citalopram hydrobromide solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
C-057 Citalopram hydrobromide solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
C-090 Citalopram-D6 hydrobromide solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
C-118 Clomipramine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
C-116 Clomipramine-d3 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-906 Desipramine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-903 Desipramine-D3 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-116 Desipramine-D3 hydrochloride solution 1.0 mg/mL in methanol (as free base), certified reference material, Cerilliant®
D-074 N-Desmethylcitalopram-D3 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-047 N-Desmethylcitalopram hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-113 N-Desmethylclomipramine-D3 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, Cerilliant®
D-916 N-Desmethylclomipramine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-007 Desmethyldoxepin solution cis/trans, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
D-075 N-Desmethyldoxepin-D3 hydrochloride solution cis/trans, 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-084 Desmethylene Paroxetine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-164 N-Desmethylmirtazapine-D4 solution 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL New
D-086 N-Desmethylmirtazapine solution 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
D-012 (±)-N-Desmethylselegiline solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
D-114 N-Desmethyltrimipramine-D3 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, Cerilliant®
D-920 N-Desmethyltrimipramine maleate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
V-027 (±)-O-Desmethylvenlafaxine-D6 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
V-045 O-Desmethylvenlafaxine solution 1.0 mg/mL in methanol, certified reference material, Cerilliant®
V-007 O-Desmethylvenlafaxine solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
D-173 Dothiepin HCl (cis/trans) solution 1 mg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
D-927 Doxepin hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-060 Doxepin-D3 hydrochloride solution (cis/trans), 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-115 Doxepin-D3 (cis/trans) hydrochloride solution 1.0 mg/mL in methanol (as free base), certified reference material, Cerilliant®
D-044 Duloxetine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
D-068 Duloxetine-D3 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
34012 Fluoxetine hydrochloride VETRANAL, analytical standard
F-918 Fluoxetine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
F-919 Fluoxetine-D6 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
F-038 Fluoxetine-D6 oxalate solution 1.0 mg/mL in methanol (as free base), certified reference material, Cerilliant®
F-040 Fluvoxamine maleate 1.0 mg/mL in methanol (as free base), certified reference material, Cerilliant®
F-045 Fluvoxamine-D3 maleate solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
H-118 8-Hydroxy Amoxapine solution 1.0 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
H-131 8-Hydroxy Amoxapine-D8 solution 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
H-062 (±)-Hydroxybupropion-D6 solution 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
H-066 (±)-Hydroxybupropion solution 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
H-117 4-Hydroxyduloxetine acetate solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
H-102 4-Hydroxyduloxetine-beta-D-glucuronide solution 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant® New
I-902 Imipramine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
I-903 Imipramine-D3 maleate solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
L-041 Lofepramine hydrochloride 1.0 mg/mL in methanol (with 1% 1 M HCL; as free base), certified reference material, Cerilliant®
M-920 Maprotiline hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
M-203 Maprotiline-D3 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 1 mL
M-919 Mianserin hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
M-901 Mianserin-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
M-145 Milnacipran hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
M-209 Milnacipran-D10 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
M3157 Minaprine dihydrochloride analytical standard
M-128 Mirtazapine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
M-191 Mirtazapine-D3 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-119 Nefazodone hydrochloride solution 1 mg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
N-122 Nordothiepin HCl (cis/trans) solution 1 mg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®
N-923 Norfluoxetine oxalate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-922 Norfluoxetine-D6 oxalate solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-102 Norfluoxetine-D6 oxalate solution 1.0 mg/mL in methanol (as free base), certified reference material, Cerilliant®
N-084 Norsertraline-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-049 (±)-Norsertraline hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-907 Nortriptyline hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-090 Nortriptyline-D3 hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-902 Nortriptyline-D3 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
P-916 Paroxetine maleate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
P-915 Paroxetine-D6 maleate solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
P-130 Perphenazine solution 1 mg/mL in methanol (
), certified reference material, ampule of 1 mL, Cerilliant®
P-131 Perphenazine-D8 solution 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
P-139 Phenelzine Sulfate solution 1 mg/mL (0.1% 1M HCl in Methanol (v/v), (as free base)), certified reference material, ampule of 1 mL, Cerilliant®
P-903 Protriptyline hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
P-088 Protriptyline-d3 hydrochloride 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
S-003 R(-)-Selegiline solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
S-021 Sertraline hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
S-026 (±)-Sertraline-D3 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
T-030 Trazodone hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
T-079 Trazodone-D6 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
T-129 Triflupromazine-D6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 1 mL
T-904 Trimipramine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
T-071 Trimipramine-D3 maleate solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
V-004 Venlafaxine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
V-009 Venlafaxine-D6 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
V-037 Venlafaxine-D6 hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
V-076 Vilazodone hydrochloride solution 1 mg/mL (Methanol:DMSO (90:10) (v/v)), certified reference material, ampule of 1 mL, Cerilliant®
V-028 Vilazodone-D4 hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
V-072 Vortioxetine-D8 solution 100 μg/mL (1% 1M HCl in Methanol (v/v)), certified reference material, ampule of 1 mL, Cerilliant®