Fentanyls
Fentanyls are rapid-acting synthetic μ-opioid receptor agonists that depress the central nervous system (CNS) and may alleviate pain without causing loss of consciousness. Therefore, traditional fentanyls such as fentanyl, remifentanil and sufentanil are used in pain medication and anesthesia. The emergence of fentanyls as drugs of abuse represents the greatest challenge to current forensic toxicology. Recently, a huge number of new fentanyl structural variants, also known as designer fentanyls, have appeared on the illicit drug market. Often mixed with traditional opioid drugs, these highly potent fentanyl analogues have caused harmful intoxications and dramatically increased opioid related mortality in the United States, Europe and Asia. Over 90 overdose deaths in the U.S. occur each day due to opioids, particularly from fentanyl and its synthetic analogs. Abuse of opioids and fentanyls has been declared as a “national public health emergency” in the U.S., leading to stricter governmental regulations on opioid prescription, and new DEA regulations for fentanyl analogs. In the United States, the Drug Enforcement Agency placed the broadly defined class of "Fentanyl-Related Substances" on the list of Schedule I drugs in 2018, making it illegal to manufacture, distribute, or possess fentanyl analogs. Due to the very high potency of some fentanyl analogues, forensic testing labs performing LC-MS/MS fentanyl testing are facing the challenge of detecting minimal trace amounts of drug in biological samples while ensuring laboratory safety. To help address these safety challenges, we provide Certified Spiking Solutions® of the most potent fentanyl analogues, such as carfentanyl, in an ampoule additionally protected in a “safety can”, ensuring safe transport and handling in the lab.

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A-109 Acetyl fentanyl solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
    • A-129 Acetyl fentanyl solution 50 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
    • A-110 Acetyl fentanyl-13C6 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
    • A-130 Acetyl fentanyl-13C6 solution 50 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®
    • A-115 Acetyl norfentanyl oxalate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
    • A-116 Acetyl norfentanyl-13C6 oxalate solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
    • A-140 Acryl fentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • A-156 Acryl fentanyl-D5 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • A-178 Acryl fentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • A-071 Alfentanil hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
    • A-139 4-ANPP solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • A-157 4-ANPP-D5 solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • A-177 4-ANPP-13C6 solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • B-079 Benzylfentanyl hydrochloride solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • B-080 Benzylfentanyl-D3 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • H-139 (±)-beta-Hydroxythiofentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • B-066 Butyryl fentanyl solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • B-081 Butyryl fentanyl-D5 solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • B-087 Butyryl fentanyl-13C6 solution 100 μg/mL in methanol (
    ), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-203 Carfentanil-13C6 oxalate solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-162 Carfentanil Oxalate solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-163 Carfentanil-D5 Oxalate solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-191 4-Chlorofuranyl fentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-192 4-Chlorofuranyl fentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-185 4-Chloroisobutyryl fentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-186 4-Chloroisobutyryl fentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-187 Crotonyl fentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-189 Cyclohexyl fentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-190 Cyclohexyl fentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-182 Cyclopentyl fentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-183 Cyclopentyl fentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-177 Cyclopropyl fentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • C-204 Cyclopropyl fentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • F-013 Fentanyl solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
    • F-002 Fentanyl solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
    • F-001 Fentanyl-D5 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
    • F-072 Fentanyl-13C6 solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • F-074 para-Fluorobutyryl fentanyl-13C6 solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • F-048 p-Fluorobutyryl fentanyl (PFBF) solution 100 μg/mL in methanol (
    ), certified reference material, ampule of 0.5 mL, Cerilliant®
    • F-054 o-Fluorofentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • F-077 o-Fluorofentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • F-049 p-Fluorofentanyl solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • F-059 para-Fluorofentanyl-D3 solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • F-070 para-Fluorofentanyl-13C6 solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • F-050 4-Fluoro-isobutyryl fentanyl solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • F-058 4-Fluoroisobutyryl fentanyl-13C6 solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • F-046 Furanyl fentanyl hydrochloride solution 100 μg/mL in methanol (as free base), ampule of 0.5 mL, certified reference material, Cerilliant®
    • F-053 Furanyl fentanyl-D5 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • H-130 (±)-β-Hydroxythiofentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • I-038 Isobutyryl fentanyl hydrochloride solution 100 μg/mL in methanol (as a free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • I-041 Isobutyryl fentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • M-200 Methoxyacetyl fentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • M-213 para-Methoxybutyryl fentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • M-216 para-Methylacetyl fentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • M-217 para-Methylacetyl fentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • M-194 (±)-cis-3-Methylfentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • M-225 3-Methyl fentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • M-214 α-Methylfentanyl hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL
    • N-129 Norcarfentanil-13C6 oxalate solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • N-114 Norcarfentanil oxalate oxalate salt solution 100 μg/mL in methanol (as a free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • N-031 Norfentanyl oxalate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
    • N-030 Norfentanyl-D5 oxalate solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
    • N-055 Norfentanyl-D5 oxalate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
    • N-130 Norfentanyl-13C6 oxalate solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • O-047 Ocfentanil solution 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®
    • R-024 Remifentanil hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, Cerilliant®
    • R-034 Remifentanil-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • R-026 Remifentanil acid solution 100 μg/mL in acetonitrile, certified reference material, Cerilliant®
    • S-018 Sufentanil-D5 solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
    • S-008 Sufentanil Citrate solution 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
    • T-131 Tetrahydrofuranyl fentanyl-13C6 hydrochloride solution 100 μg/mL in methanol ((as free base)), certified reference material, ampule of 0.5 mL, Cerilliant®
    • V-048 Valeryl fentanyl hydrochloride solution 100 μg/mL in methanol (as a free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • V-068 Valeryl fentanyl-D5 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®
    • V-077 Valeryl fentanyl-13C6 hydrochloride solution 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®