Intermediate Polar Capillary GC Columns

Intermediate polar GC columns are made with phases that incorporate both non-polar and polar elements. Thus, they are commonly used to provide alternate selectivity to non-polar and polar columns. Elution order is determined by differences in the overall effects of possible interactions.
  • Interactions are strongly dispersive (van der Waals forces). The greater the phenyl content of the phase, the stronger the interactions.
  • Phases with phenyl functional groups can also undergo π-π, dipole-dipole, and dipole-induced dipole interactions. The greater the phenyl content, the stronger these interactions.
  • Phases with cyanopropyl functional groups can also undergo strong dipole-dipole and moderate basic interactions. The greater the cyanopropyl content, the greater these interactions.