Astec® P-CAP

P-CAP can be used for normal phase separation of racemic mixtures; it has high stability, high sample loading capacity (suitable for preparative scale-up), and no memory effect.

This CSP technology is based on the reproducible polymerization of a cyclic diamine from surface of silica. This method offers maximum protection of the silica and excellent availability of the short chain polymer ligand that ensures high capacity. Preparative separations can be run in a variety of solvents (without any large impact on selectivity) to meet solubility requirements. As a result of the juxtaposition of the binding sites, molecules with two or more functional groups demonstrate the best selectivity. Separations have been run in pure acetone, heptane/ethanol, dichloromethane/methanol and ethylacetate.

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Particle Size

Length × I.D.

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31024AST Astec® (R,R) P-CAP Chiral HPLC Column 5 μm
25 cm × 4.6 mm
21150AST Supelguard Guard Cartridge Holder