Attention:

Certain features of sigmaaldrich.com will be down for maintenance Saturday afternoon/evening, February 24th starting at 3:00 pm CT until 9:00 pm CT.

Please note that you still have telephone and email access to our local offices. We apologize for any inconvenience.

HPLC & FPLC Columns for Biopolymer Separations

Biomolecules and the matrixes in which they are analyzed are often complex. To accommodate the complexity and maintain biological activity, if required, many different chromatographic techniques have been employed. We have chosen to include in our product offering select columns and media from the major separation modes, including
  • Reversed-phase (RP)
  • Size exclusion chromatography (SEC) - Gel filtration chromatography (GFC)
  • Size exclusion chromatography (SEC) - Gel permeation chromatography (GPC)
  • Ion-exchange chromatography (IEX)
  • Hydrophobic interaction chromatography (HIC)
  • Affinity chromatography
  • Hydrophilic interaction chromatography (HILIC)
Each of these modes and our corresponding products are described in their respective sections that follow.