Pharmacopoeia & Metrological Institutes Standards

Sigma-Aldrich distributes Chemical Reference Substances and Reference Standards from the world’s three leading pharmacopoeias: the United States Pharmacopoeia (USP), the European Pharmacopoeia (EP), and the British Pharmacopoeia (BP). Also available are the internationally recognized National Metrology Institute standards including BAM, NIST, NMIA and IRMM/BCR. These analytical standards can be used for a variety of method verification practices including instrument qualification and calibration, analytical method validation, system suitability testing, assays and quality control checks.

Important update on USP Primary Standards

We are pleased to announce that the United States Pharmacopeia (USP) has recently formed an agreement with Merck KGaA for the company to become an Authorized Distributor of USP Reference Standards in most countries in Europe.

As a worldwide leading supplier to the global Life Science industry, we provide scientists and engineers with best-in-class lab materials, technologies and services. Expanding our provision of USP Primary Standards allows us to maintain the level of quality products and service that you have come to expect from us. Stock is maintained in our warehouse in Germany for many of the products that are currently available through us; you can find the entire list of USP Reference Standards for sale here.

For any questions, please contact your local sales representative or email

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