HPLC

LC-MS Solvents and Reagents

New LC-MS systems have raised the bar on the purity expectations of chemicals used for sample preparation, mobile phases and post-column additives. Alkali ions, plasticizers and surfactants interfere strongly with LC-MS by causing higher background noise and the formation of adducts. Sigma-Aldrich has developed and introduced many solvents, additives and reagents that are specifically designed to meet the requirements of high-purity and consistency.