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Hygiene standards in a production environment are directly linked to the microbiological safety and quality of the finished products. To protect consumers, several government agencies have developed methods, including EU cGMP, U.S. FDA Aseptic Guidance, and USP <1116>, which apply to regulate industries like pharmaceutical, cosmetics, food, and beverages. [Speak to a Specialist](https://www.sigmaaldrich.com/CA/en/products/industrial-microbiology/viable-air-samplers/speak-to-a-specialist-microbial-air-sampling) * * * ## Related Products Slide 1 of 21 1 of 5 [ \ Millipore \ 1.46783 \ Tryptic Soy Agar - Ready-to-use Contact Plates](https://www.sigmaaldrich.com/CA/en/product/mm/146783) Quick View [ \ Millipore \ 1.46786 \ Tryptic Soy Agar - Ready-to-use Settle Plates](https://www.sigmaaldrich.com/CA/en/product/mm/146786) Quick View [ \ Millipore \ 63003BC \ FLASH® Allergen-Indicator Protein Test](https://www.sigmaaldrich.com/CA/en/product/sial/63003bc) Quick View [ \ Millipore \ 1.31200 \ HY-RiSE® Color Hygiene Test Strip](https://www.sigmaaldrich.com/CA/en/product/mm/131200) Quick View [ \ Millipore \ MYSK10025 \ Yeast and Mold Test Kit](https://www.sigmaaldrich.com/CA/en/product/mm/mysk10025) Quick View [ \ Millipore \ MSSK10025 \ HPC Total Count Test Kit](https://www.sigmaaldrich.com/CA/en/product/mm/mssk10025) Quick View [ \ Millipore \ 146798 \ Tryptic Soy Agar - Ready-to-use Contact Plates](https://www.sigmaaldrich.com/CA/en/product/mm/146798) Quick View [ \ Millipore \ 146799 \ Tryptic Soy Agar - Ready-to-use Settle Plates](https://www.sigmaaldrich.com/CA/en/product/mm/146799) Quick View [ \ Millipore \ 146800 \ Tryptic Soy Agar - Ready-to-use Settle Plates](https://www.sigmaaldrich.com/CA/en/product/mm/146800) Quick View [ \ Millipore \ 1.02136 \ Contact C](https://www.sigmaaldrich.com/CA/en/product/mm/102136) Quick View [ \ Millipore \ 1.02137 \ Contact E](https://www.sigmaaldrich.com/CA/en/product/mm/102137) Quick View [ \ Millipore \ 1.02139 \ Envirocheck™ Contact YM(R)](https://www.sigmaaldrich.com/CA/en/product/mm/102139) Quick View [ \ Millipore \ MCSK10025 \ Coli-Count™ Test Kit](https://www.sigmaaldrich.com/CA/en/product/mm/mcsk10025) Quick View [ \ Millipore \ 1.46787 \ Tryptic Soy Agar - Ready-to-use Settle Plates](https://www.sigmaaldrich.com/CA/en/product/mm/146787) Quick View [ \ Millipore \ 1.46797 \ Tryptic Soy Agar - Ready-to-use Contact Plates](https://www.sigmaaldrich.com/CA/en/product/mm/146797) Quick View [ \ Millipore \ 146800 \ Tryptic Soy Agar - Ready-to-use Settle Plates](https://www.sigmaaldrich.com/CA/en/product/mm/146800) Quick View [ \ Millipore \ 1.46804 \ Vegetable Peptone Agar](https://www.sigmaaldrich.com/CA/en/product/mm/146804) Quick View [ \ Millipore \ 1.02136 \ Contact C](https://www.sigmaaldrich.com/CA/en/product/mm/102136) Quick View [ \ Millipore \ 1.02137 \ Contact E](https://www.sigmaaldrich.com/CA/en/product/mm/102137) Quick View [ \ Millipore \ 1.02139 \ Envirocheck™ Contact YM(R)](https://www.sigmaaldrich.com/CA/en/product/mm/102139) Quick View [ \ Millipore \ MCSK10025 \ Coli-Count™ Test Kit](https://www.sigmaaldrich.com/CA/en/product/mm/mcsk10025) Quick View * * * ## Featured Categories [](https://www.sigmaaldrich.com/CA/en/products/industrial-microbiology/viable-air-samplers) [Environmental Monitoring and Aseptic Process Simulation](https://www.sigmaaldrich.com/CA/en/products/industrial-microbiology/viable-air-samplers) Explore versatile air samplers based on various principles for tailored technology solutions. Designed for food, cleanrooms, hazardous areas, and more. [Shop Products](https://www.sigmaaldrich.com/CA/en/products/industrial-microbiology/viable-air-samplers) [](https://www.sigmaaldrich.com/CA/en/products/industrial-microbiology/hygiene-monitoring-instruments-samplers-tests-and-accessories) [Hygiene Monitoring](https://www.sigmaaldrich.com/CA/en/products/industrial-microbiology/hygiene-monitoring-instruments-samplers-tests-and-accessories) Hygiene monitoring verifies the effectiveness of your sanitization routine using methods like ATP testing, NAD testing, protein testing or swab sampling for food and beverage HACCP and cannabis microbiology testing. [Shop Products](https://www.sigmaaldrich.com/CA/en/products/industrial-microbiology/hygiene-monitoring-instruments-samplers-tests-and-accessories) * * * Overview Related Articles & Protocols Support ## [](https://www.sigmaaldrich.com)Traditional Surface Monitoring To ensure the safety of a product, it is key to monitor the cleanliness of surfaces in the production area, such as tables, walls, or doors, and in isolators and cleanrooms. These surfaces and areas must be free of microorganisms to reduce the risk of cross-contamination, which could make the product unsafe for use or consumption.  Aseptic and controlled environments require frequent monitoring by surface sampling methods. Flat surfaces can be sampled by pressing contact plates or slides on the surface with uniform and steady pressure for a few seconds. The sample plates or slides are then incubated for the microorganisms to grow, before enumerating the grown bacteria cultures. The incubation conditions differ depending on microflora composition and regulatory requirements. Curved surfaces and hard-to-access areas can be monitored by the swab test method. ## [](https://www.sigmaaldrich.com)Rapid Surface Monitoring Manufacturers who require fast results can use rapid methods to quantify microbial residue post-sanitation and pre-operation. Such methods include colorimetric based assays requiring no instrument or sampling swabs requiring an instrument reader such as a luminometer. The need for rapid quality control methods is especially high in the food and beverages industry. Due to the perishable nature of their manufactured goods, but also in other industries to keep up with increasing production demand. ## [](https://www.sigmaaldrich.com)Personnel Monitoring Personnel monitoring is performed to ensure the maintenance of the sterile environment. The majority of contamination within a facility can be traced to humans working in cleanrooms. Specific procedures for gowning, and sterilizing, need to be followed by the personnel before entering and exiting the aseptic cleanroom. [](https://www.sigmaaldrich.com/documents-search) [Looking for More Specific Information?](https://www.sigmaaldrich.com/documents-search) Visit our document search for data sheets, certificates and technical documentation. [Find Documents](https://www.sigmaaldrich.com/documents-search) ## Related Articles - [Contact Plates and Swabs for Personnel and Surface Monitoring](https://www.sigmaaldrich.com/CA/en/technical-documents/technical-article/microbiological-testing/surface-and-personnel-testing/contact-plates-and-swabs) Explore our range of contact plates and swabs for microbiological testing. Ideal for environmental monitoring in cleanrooms and controlled areas, our products ensure reliable surface and personnel testing to minimize contamination risks. - [Sterile Environmental Swabs](https://www.sigmaaldrich.com/CA/en/technical-documents/technical-article/microbiological-testing/surface-and-personnel-testing/icr-swab) The ICR-Swab is a swab system for environmental monitoring of dry surfaces, such as filling needles, equipment recesses, uneven surfaces and tubing in clean rooms and isolators. - [Bacterial Contamination Detection with ICR Swabs](https://www.sigmaaldrich.com/CA/en/technical-documents/technical-article/microbiological-testing/surface-and-personnel-testing/detection-of-low-bacterial-contamination) The ICR swabs and ICR contact plates are designed for environmental monitoring i.e., detection and enumeration of microbial contamination on dry, flat, and hard-to-access surfaces in cleanrooms and isolators. - [Environmental Sample Pre Storage on Counting Results](https://www.sigmaaldrich.com/CA/en/technical-documents/technical-article/microbiological-testing/viable-air-monitoring/environmental-sample-pre-storage-on-counting-results) Microbial monitoring; environmental monitoring; interim storage; ICR contact plates; contact plates; TSA w. LTHThio Contact ICR+ - [IsoBag® Rapid Transfer Solution Optimizes Your Environmental Monitoring Workflow](https://www.sigmaaldrich.com/CA/en/technical-documents/technical-article/microbiological-testing/viable-air-monitoring/environmental-monitoring-isobags) IsoBag® ease the environmental monitoring workflow in aseptic production isolator - [See All (4)](https://www.sigmaaldrich.com/CA/en/search/facet-search?focus=sitecontent&term=facet-search) ### Find More Articles and Protocols Enter Keywords Search ## Related Webinars Slide 1 of 3 [![A close-up image of a hand wearing a purple glove holding a barcode scanner aimed at a circular device displaying a QR code. The background is a vibrant blue, enhancing the focus on the scanning action and the technology being used.](https://www.sigmaaldrich.com/content/dam/cms-commons/sigmaaldrich/marketing/global/images/applications/microbiological-testing/mas-100-sirius-640x360.jpg "

Getting Equipped for the Future of Air Monitoring

")](https://www.sigmaaldrich.com/CA/en/collections/webinars/mas-100-sirius-microbial-air-sampler) [Getting Equipped for the Future of Air Monitoring](https://www.sigmaaldrich.com/CA/en/collections/webinars/mas-100-sirius-microbial-air-sampler) Join our event to discover a microbial air sampler that helps you prepare for the challenges of the future in pharmaceutical manufacturing. [![A close-up image of a gloved hand placing a sealed petri dish into a circular opening of a laboratory device. The device features a metal rim and a bright blue background, emphasizing a sterile and controlled environment for scientific work.](https://www.sigmaaldrich.com/content/dam/cms-commons/sigmaaldrich/marketing/global/images/applications/microbiological-testing/gloveless-isolators-640x360.jpg "

Navigating Cleanroom Compliance for Safe Material Transfer

")](https://www.sigmaaldrich.com/CA/en/collections/webinars/navigating-cleanroom-compliance-for-safe-material-transfer) [Navigating Cleanroom Compliance for Safe Material Transfer](https://www.sigmaaldrich.com/CA/en/collections/webinars/navigating-cleanroom-compliance-for-safe-material-transfer) Learn about environmental monitoring aspects to consider when materials need to be transferred into controlled areas. [![A laboratory image featuring a metal apparatus with a circular opening displaying a series of petri dishes inside. In the foreground, a pair of forceps is holding a petri dish, showcasing a hands-on approach to scientific experimentation. The background is a bright yellow, enhancing the focus on the equipment and the petri dish.](https://www.sigmaaldrich.com/content/dam/cms-commons/sigmaaldrich/marketing/global/images/applications/microbiological-testing/safe-material-transfer-640x360.jpg "

Automated Environmental Monitoring in Gloveless Isolators

")](https://www.sigmaaldrich.com/CA/en/collections/webinars/enhancing-automated-environmental-monitoring-in-gloveless-isolators) [Automated Environmental Monitoring in Gloveless Isolators](https://www.sigmaaldrich.com/CA/en/collections/webinars/enhancing-automated-environmental-monitoring-in-gloveless-isolators) Learn more about the latest advancements in automation within fill and finish processes. ## How Can We Help In case of any questions, please submit a [customer support request](https://www.sigmaaldrich.com/CA/en/support/customer-support) or talk to our customer service team: Email [[email protected]](mailto:[email protected]) or call +1 (800) 244-1173 ## Additional Support - [Calculators & Apps](https://www.sigmaaldrich.com/CA/en/support/calculators-and-apps) Web Toolbox - science research tools and resources for analytical chemistry, life science, chemical synthesis and materials science. - [Customer Support Request](https://www.sigmaaldrich.com/CA/en/support/customer-support) Customer support including help with orders, products, accounts, and website technical issues. - [FAQ](https://maestro.my.site.com/knowledgeportal/s/) Explore our Frequently Asked Questions for answers to commonly asked questions about our products and services. * * * __Featured Articles__ [Contact Plates and Swabs for Personnel and Surface Monitoring](https://www.sigmaaldrich.com/CA/en/technical-documents/technical-article/microbiological-testing/surface-and-personnel-testing/contact-plates-and-swabs) Explore our range of contact plates and swabs for microbiological testing. Ideal for environmental monitoring in cleanrooms and controlled areas, our products ensure reliable surface and personnel testing to minimize contamination risks. [Sterile Environmental Swabs](https://www.sigmaaldrich.com/CA/en/technical-documents/technical-article/microbiological-testing/surface-and-personnel-testing/icr-swab) The ICR-Swab is a swab system for environmental monitoring of dry surfaces, such as filling needles, equipment recesses, uneven surfaces and tubing in clean rooms and isolators. [Bacterial Contamination Detection with ICR Swabs](https://www.sigmaaldrich.com/CA/en/technical-documents/technical-article/microbiological-testing/surface-and-personnel-testing/detection-of-low-bacterial-contamination) The ICR swabs and ICR contact plates are designed for environmental monitoring i.e., detection and enumeration of microbial contamination on dry, flat, and hard-to-access surfaces in cleanrooms and isolators. [Environmental Sample Pre Storage on Counting Results](https://www.sigmaaldrich.com/CA/en/technical-documents/technical-article/microbiological-testing/viable-air-monitoring/environmental-sample-pre-storage-on-counting-results) Microbial monitoring; environmental monitoring; interim storage; ICR contact plates; contact plates; TSA w. LTHThio Contact ICR+ Top __Sign In To Continue__ To continue reading please sign in or create an account. 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Services - [Contract Manufacturing](https://www.sigmaaldrich.com/CA/en/services/contract-manufacturing) - [ADC & Bioconjugation](https://www.sigmaaldrich.com/CA/en/services/contract-manufacturing/adc-bioconjugation) - [Diagnostic OEM & CMO Services](https://www.sigmaaldrich.com/CA/en/services/ivd-development-manufacturing/diagnostic-oem-cmo) - [mRNA & LNP](https://www.sigmaaldrich.com/CA/en/services/contract-manufacturing/mrna-and-lnp-formulation-ctdmo-services) - [Lipids CDMO Services](https://www.sigmaaldrich.com/CA/en/services/contract-manufacturing/mrna-and-lnp-formulation-ctdmo-services/lipids-cdmo-services) - [Lipid Nanoparticle CDMO Service](https://www.sigmaaldrich.com/CA/en/services/contract-manufacturing/mrna-and-lnp-formulation-ctdmo-services/lipid-nanoparticle-cdmo-services) - [Small Molecule](https://www.sigmaaldrich.com/CA/en/services/contract-manufacturing/small-molecule) - [Activated Polyethylene Glycol (PEGs)](https://www.sigmaaldrich.com/CA/en/services/contract-manufacturing/peg) - 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