Canadian Academic pricing for RNAi

Innovation through Worldwide Academic Support and Partnership

Sigma-Aldrich is pleased to offer the Academic Pricing and RNAi Partnership Programs, which are designed to make the renowned TRC1 and TRC2 MISSION®shRNA collections and other RNAi-related technologies more accessible to researchers at academic institutions. We are dedicated to providing optimal service to academic researchers as well as our industry partners.

Our website not only contains background information and search tools for the TRC1 & TRC2 libraries, but also contains a great deal of related technology information, educational resources, and protocols. Information follows below about our Academic Pricing Program and our RNAi Partnership Program for academic institutes and core facilities.

General Pricing Guidelines

Sigma is pleased to introduce a tiered discounting structure when you buy multiple clones of one gene.  We recommend buying multiple individual constructs targeting different regions of the gene sequence.  The general pricing guidelines for ordering multiple clones of a single gene are listed below.

Available number of clones per gene Minimum number purchased To receive a volume discount*
>5 5 60%
4 4 50%
3 3 40%
<3   None**
1   None**

*Academic or RPP pricing discounts would apply after the discounts below are applied.
 **Academic or RPP pricing would apply, however.

Academic Pricing Program

Note: Specific guidelines below are noted for US and Canada. For all other countries, please contact your local Sigma office for academic pricing on MISSION products.
Special academic pricing is available upon request for academic institutions worldwide. Upon your request, we will set up your institution's pricing so that it is visible on the web when you are logged into your online ordering account. Institution wide requests may be made through your local biotech sales representative or by emailing us at For one-time orders, we can provide quotation numbers that can be referenced when you place your online order.  Academic Pricing provides a discount off of our list pricing.  The highest level of discounted pricing is available through our RNAi Partnership Program. For additional pricing information or to set up your account, please email us at

Special pricing on all sizes and formats of the MISSION® TRC collection is available.

  • Entire libraries
  • Gene family sets
  • Single clones and gene sets 
  • Glycerol stocks
  • Purified plasmid DNA
  • Lentiviral particles

The following institutions have already been set up to receive academic pricing from Sigma-Aldrich. Once you have set up your online ordering account that references your Sigma account number, you will be on your way to ordering at special pricing. After logging in, click here to start searching and ordering.

Canadian Institutions

  • University of Toronto
  • University of British Columbia
  • University of Alberta
  • McGill University
  • University Health Network
  • University of Montreal
  • Hospital for Sick Children
  • University of Laval
  • Unviersity of Guelph
  • University of Western Ontario
  • University of Calgary
  • McMaster University
  • University of Manitoba
  • Dalhousie University
  • University of Sherbrooke
  • Mount Sinai Hospital
  • University of Saskatchewan
  • The Ottawa Hospital
  • Queen's University
  • CHUQ
  • Alberta Cancer Board
  • Jewish General Hospital
  • Ottawa Hospital - Civic Campus
  • CHUM
  • University of Ottawa

American Institutions

  • Alabama A&M University
  • Albert Einstein College of Medicine (Yeshiva University)
  • Baylor College of Medicine
  • Beth Israel Deaconess Medical Center
  • Boston College
  • Brandeis University
  • Brown University
  • California Institute of Technology
  • Carnegie-Institute of Washington
  • Carnegie-Mellon University
  • Case Western Reserve University
  • City of Hope
  • Columbia University
  • Cornell University
  • Dana Farber Cancer Institute
  • Dartmouth College
  • Drexel University
  • Duke University
  • Emory University
  • Florida Atlantic University
  • Forsyth Institute
  • Harvard University
  • Indiana University
  • Johns Hopkins University
  • Joslin Diabetes Center
  • Massachusetts College of Pharmacy
  • Massachusetts Eye & Ear Infirmary
  • Massachusetts General Hospital
  • Massachusetts Institute of Technology
  • MD Anderson Cancer Center
  • Medical College of Georgia
  • Memorial Sloan-Kettering Cancer Center
  • Mount Saint Vincent University
  • Mount Sinai School of Medicine, NYC
  • National Cancer Institute
  • National Institutes of Health (NIH)
  • NE Regional Primate Center
  • New York Institute for Basic Research
  • New York Medical College
  • New York Presbyterian Hospital
  • New York Structural Biology Center
  • New York University
  • Northwestern University
  • Ohio State University
  • Partners Healthcare
  • Pennsylvania State University
  • Purdue University
  • Rhode Island Hospital
  • Rockefeller University
  • Salk Institute
  • Scripps Research Institute
  • Schepens Eye Research Institute
  • Stanford University
  • St. Jude Children's Research Hospital
  • SUNY
  • University of Alabama
  • University of Arkansas
  • University of California, Berkeley
  • University of California, Davis
  • University of California, Irvine
  • University of California, Los Angeles
  • University of California, San Diego
  • University of California, San Francisco
  • University of Chicago
  • University of Colorado
  • University of Maryland
  • University of Massachusetts
  • University of Minnesota, Duluth
  • University of Minnesota, Twin Cities
  • University of New Hampshire
  • University of North Carolina, Chapel Hill
  • University of Pennsylvania
  • University of Pittsburgh
  • University of Rhode Island
  • University of San Diego
  • University of South Alabama
  • University of Southern California
  • University of Texas, Arlington
  • University of Texas, Austin
  • University of Texas, Brownsville
  • University of Texas, Dallas
  • University of Texas, Medical Branch
  • University of Texas, San Antonio
  • University of Texas, Tyler
  • University of Toledo
  • University of Utah
  • University of Vermont
  • University of Virginia
  • University of Washington, Seattle
  • University of Washington Medical Center
  • University of Wisconsin, Madison
  • Wayne State University
  • Yale University

The RNAi Partnership Program

Special RNA Partnership pricing is available upon request for select institutions and core facilities. This program provides even deeper discounting for academic institutes as well as a variety of ways to partner with Sigma-Aldrich. For pricing and membership opportunities with this program, please contact your local biotech sales representative or email us at You may already be able to take advantage of program benefits. Please refer to the list below to determine current eligibility.

The following institutions have already been set up in The RNAi Partnership Program from Sigma-Aldrich.

  • Academic Medical Center (Netherlands)
  • Burnham Institute
  • CEA Functional Genomics Program (France)
  • Cincinnati's Children's Hospital Medical Center
  • Cleveland Clinic
  • DKBW, University of Basel (Switzerland)
  • ErasmusMC (Netherlands)
  • Hebrew University (Israel)
  • Hong Kong University
  • Inserm U 601.Nantes.France.
  • IRB Barcelona (Spain)
  • Leiden University Medical Center (Netherlands)
  • Mayo Clinic
  • Moore's Cancer Center-UCSD
  • National Heart, Lung and Blood Institute
  • Newcastle University (UK)
  • Princeton University
  • Rutgers University
  • St. Jude Children’s Research Hospital
  • The Pharmacology Institut of Toulouse in France
  • The Wistar Institute
  • Tufts University
  • University College London (UK)
  • University of Bern, Department of Clinical Research (Switzerland)
  • University of Debrecen (Hungary)
  • University of Edinburgh
  • University of Helsinki (Finland)
  • University of Illinois System
  • University of Michigan
  • University of Pennsylvania
  • UT Southwestern Medical Center
  • Vanderbilt University
  • Washington University of St. Louis

The program combines any number of benefits/options for researchers including, but not limited to:

  • Institution-wide partnership pricing on all sizes and formats of the MISSION TRC collections:
    • Entire libraries
    • Gene family sets
    • Single clones and gene sets 
    • Glycerol stocks
    • Purified plasmid DNA
    • Lentiviral particles
  • Access to a broad portfolio of key intellectual property for MISSION purchases.
  • Collaborative relationships between Sigma-Aldrich scientists and other Partnership Program Members.
  • Early access to new technologies and libraries through Sigma-Aldrich/Proligo and our partnerships with TRC, Oxford BioMedica, Benitec, Panomics and others.
  • Both siRNA and shRNA technology platforms available.
  • Wide offering of products from Sigma-Aldrich including:
    • shRNA
    • siRNA
    • Quantitative PCR technologies/reagents
    • Primers/probes
    • Extensive antibody offering
    • Protein quantitation and characterization products
    • Cell culture
    • Transfection reagents
  • High quality service & support from Sigma-Aldrich
    • Dedicated ordering and technical service support for RNAi
    • Superior technical expertise for your entire workflow
    • Skilled R&D scientists available for consultation
    • Quality assurance through bioinformatics, robotics, and more
    • Site visits to partner core facilities worldwide
  • Access to our validation data as available

For more information on The RNAi Partnership Program, email us at

Are you interested in purchasing an entire gene library or a custom gene family set? Please check with your local sales representative or email us at for more information.

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For questions about the library, pricing and quotes or other concerns, please e-mail us at:

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