Certificate Of Analysis
Product Name R(+)-Verapamil monohydrochloride hydrate,
≥98% (HPLC), powder
Product Number V106
Product Brand SIGMA
CAS Number 38176-02-2 (anhydrous)
Molecular Formula C27H38N2O4 · HCl · xH2O
Molecular Weight 491.06 (anhydrous basis)
 
TEST SPECIFICATION LOT 028K46074 RESULTS
APPEARANCE WHITE SOLID
SOLUBILITY 22 MG/ML IN WATER
CARBON 65.64%
HYDROGEN 8.22%
NITROGEN 5.52%
CHLORIDE 7.01%
WATER BASED ON CHN 0.5 MOL/MOL
SPECIFIC ROTATION +7.0 DEG (C = 0.6 IN ETHANOL AT 20 DEG CELSIUS)
PROTON NMR SPECTRUM CONSISTENT WITH STRUCTURE
PURITY BY HPLC >99.0%
QC RELEASE DATE 07 SEP 2010