Human(94160) Summary: This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]
Mouse(244562) ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Rat(291923) ATP-binding cassette, subfamily C (CFTR/MRP), member 12
Zebrafish(568482) ATP-binding cassette, sub-family C (CFTR/MRP), member 12
cow(528068) ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Horse(100057417) ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Save up to 60% per TRCN when you buy a set of 5 or more with the same options.
MISSION® siRNAs have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. The Rosetta-powered siRNA design algorithm has been optimized with over 3 years of continuous development for enhanced performance in RNAi applications. New and critical siRNA design rules incorporated into the latest algorithm lead to increased target specificity and knockdown for low abundance messages.
Validated MISSION® siRNAs have been functionally validated in Hela cells by Sigma scientists to Knockdown gene expression by 75% or greater. With Validated MISSION® siRNAs, we have done the upfront validation work, so that you do not have to.
Custom Gene Products
Our expertise in DNA & RNA oligo design, chemistry and manufacturing enable Sigma Custom Products to provide a comprehensive product portfolio. Learn more about our "custom capabilities & extensive options today."
siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product #
siRNA Type
Species
NM_033226
Rosetta Predictions
human
pricing
NM_199377
Rosetta Predictions
rat
pricing
NM_172912
Rosetta Predictions
mouse
pricing
shRNA
PRODUCT TYPE
PRODUCT NAME
SPECIES
SHCLNG-NM_033226
ABCC12 MISSION shRNA Bacterial Glycerol Stock ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Human
10 Products Total
TRC Number
Price
Set Price (5+)?
Select
We do not support the configuration options you have chosen
