Human(10257) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Mouse(239273) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Rat(170924) ATP-binding cassette, subfamily C (CFTR/MRP), member 4
Zebrafish(368620) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
cow(616707) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
cow(515333) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
cow(617150) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Horse(100050431) ATP-binding cassette, sub-family C (CFTR/MRP), member 4
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MISSION® siRNAs have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. The Rosetta-powered siRNA design algorithm has been optimized with over 3 years of continuous development for enhanced performance in RNAi applications. New and critical siRNA design rules incorporated into the latest algorithm lead to increased target specificity and knockdown for low abundance messages.
Validated MISSION® siRNAs have been functionally validated in Hela cells by Sigma scientists to Knockdown gene expression by 75% or greater. With Validated MISSION® siRNAs, we have done the upfront validation work, so that you do not have to.
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siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product #
siRNA Type
Species
NM_001105515
Rosetta Predictions
human
pricing
NM_005845
Rosetta Predictions
human
pricing
NM_133411
Rosetta Predictions
rat
pricing
XM_344458
Rosetta Predictions
rat
pricing
NM_001033336
Rosetta Predictions
mouse
pricing
shRNA
PRODUCT TYPE
PRODUCT NAME
SPECIES
SHCLNG-NM_005845
VALIDATED
ABCC4 MISSION shRNA Bacterial Glycerol Stock ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Human
10 Products Total
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