Human(57016) Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]
Mouse(67861) aldo-keto reductase family 1, member B10 (aldose reductase)
Rat(296972) aldo-keto reductase family 1, member B10 (aldose reductase)
chicken(395338) aldo-keto reductase family 1, member B10 (aldose reductase)
cow(525193) aldo-keto reductase family 1, member B10 (aldose reductase)
Save up to 60% per TRCN when you buy a set of 5 or more with the same options.
MISSION® siRNAs have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. The Rosetta-powered siRNA design algorithm has been optimized with over 3 years of continuous development for enhanced performance in RNAi applications. New and critical siRNA design rules incorporated into the latest algorithm lead to increased target specificity and knockdown for low abundance messages.
Validated MISSION® siRNAs have been functionally validated in Hela cells by Sigma scientists to Knockdown gene expression by 75% or greater. With Validated MISSION® siRNAs, we have done the upfront validation work, so that you do not have to.
Custom Gene Products
Our expertise in DNA & RNA oligo design, chemistry and manufacturing enable Sigma Custom Products to provide a comprehensive product portfolio. Learn more about our "custom capabilities & extensive options today."
siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product #
siRNA Type
Species
NM_020299
Rosetta Predictions
human
pricing
NM_001013084
Rosetta Predictions
rat
pricing
NM_172398
Rosetta Predictions
mouse
pricing
shRNA
PRODUCT TYPE
PRODUCT NAME
SPECIES
SHCLNG-NM_172398
VALIDATED
AKR1B10 MISSION shRNA Bacterial Glycerol Stock aldo-keto reductase family 1, member B10 (aldose reductase)
Mouse
10 Products Total
TRC Number
Price
Set Price (5+)?
Select
We do not support the configuration options you have chosen