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GMDS

GDP-mannose 4,6-dehydratase

45 Gene Product Result for
Synonyms: GMD SDR3E1
Gene ID:
Human(2762) Summary: GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM, Aug 2009]
Mouse(218138) GDP-mannose 4, 6-dehydratase
Rat(291095) GDP-mannose 4, 6-dehydratase
Zebrafish(393461) GDP-mannose 4,6-dehydratase
cow(617688) GDP-mannose 4,6-dehydratase
Horse(100057325) GDP-mannose 4,6-dehydratase
domestic cat(101086651) GDP-mannose 4,6-dehydratase
dog(488189) GDP-mannose 4,6-dehydratase
chicken(420890) GDP-mannose 4,6-dehydratase
sheep(101101931) GDP-mannose 4,6-dehydratase
naked mole-rat(101703718) GDP-mannose 4,6-dehydratase
Gene Class: Dehydratase
Custom Gene Products
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shRNA

Type Description Species Add to Cart
 

esiRNA

Product # Description Species Add to Cart
 
EHU047091 MISSION® esiRNA esiRNA human GMDS (esiRNA1) human pricing

Custom CRISPR Plasmid

Product # Description  
 
CRISPR Custom CRISPR Plasmid for gene knockout

siRNA

siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm.
All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product # siRNA Type Species  
 
NM_001500 Rosetta Predictions human pricing
NM_001039606 Rosetta Predictions rat pricing
NM_146041 Rosetta Predictions mouse pricing
siRNA
PRODUCT # siRNA Type ? SPECIES
NM_001500 Rosetta Predictions Human
Ranking siRNA ID Sequence Start ?
1 SASI_Hs01_00170679 predicted 956
2 SASI_Hs01_00170680 predicted 644
3 SASI_Hs01_00170681 predicted 871
4 SASI_Hs01_00170683 predicted 589
5 SASI_Hs01_00170684 predicted 578
6 SASI_Hs01_00170685 predicted 429
7 SASI_Hs02_00331991 predicted 610
8 SASI_Hs01_00170686 predicted 535
9 SASI_Hs02_00331992 predicted 477
10 SASI_Hs01_00170687 predicted 403
11 SASI_Hs01_00170682 predicted 452
12 SASI_Hs01_00170688 predicted 594
siRNA
PRODUCT # siRNA Type ? SPECIES
NM_001039606 Rosetta Predictions Rat
Ranking siRNA ID Sequence Start ?
1 SASI_Rn01_00059304 predicted 206
2 SASI_Rn01_00059305 predicted 943
3 SASI_Rn01_00059306 predicted 719
4 SASI_Rn01_00059307 predicted 244
5 SASI_Rn02_00204858 predicted 996
6 SASI_Rn02_00204859 predicted 478
7 SASI_Rn01_00059308 predicted 618
8 SASI_Rn01_00059309 predicted 562
9 SASI_Rn01_00059310 predicted 784
10 SASI_Rn01_00059312 predicted 223
11 SASI_Rn01_00059311 predicted 635
12 SASI_Rn01_00059313 predicted 481
siRNA
PRODUCT # siRNA Type ? SPECIES
NM_146041 Rosetta Predictions Mouse
Ranking siRNA ID Sequence Start ?
1 SASI_Mm01_00054886 predicted 245
2 SASI_Mm01_00054887 predicted 284
3 SASI_Mm01_00054889 predicted 918
4 SASI_Mm01_00054890 predicted 658
5 SASI_Mm01_00054892 predicted 213
6 SASI_Mm01_00054893 predicted 209
7 SASI_Mm02_00341645 predicted 741
8 SASI_Mm01_00054894 predicted 912
9 SASI_Mm01_00054895 predicted 980
10 SASI_Mm02_00341646 predicted 515
11 SASI_Mm01_00054888 predicted 250
12 SASI_Mm01_00054891 predicted 252