Human(22876) Summary: The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Mouse(101490) inositol polyphosphate-5-phosphatase F
Rat(309008) inositol polyphosphate-5-phosphatase F
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MISSION® siRNAs have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. The Rosetta-powered siRNA design algorithm has been optimized with over 3 years of continuous development for enhanced performance in RNAi applications. New and critical siRNA design rules incorporated into the latest algorithm lead to increased target specificity and knockdown for low abundance messages.
Validated MISSION® siRNAs have been functionally validated in Hela cells by Sigma scientists to Knockdown gene expression by 75% or greater. With Validated MISSION® siRNAs, we have done the upfront validation work, so that you do not have to.
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siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product #
siRNA Type
Species
NM_014937
Rosetta Predictions
human
pricing
NM_198330
Rosetta Predictions
human
pricing
NM_198331
Rosetta Predictions
human
pricing
NR_003251
Rosetta Predictions
human
pricing
NR_003252
Rosetta Predictions
human
pricing
NM_001107554
Rosetta Predictions
rat
pricing
NM_178641
Rosetta Predictions
mouse
pricing
shRNA
PRODUCT TYPE
PRODUCT NAME
SPECIES
SHCLNG-NM_178641
VALIDATED
INPP5F MISSION shRNA Bacterial Glycerol Stock inositol polyphosphate-5-phosphatase F
Mouse
8 Products Total
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