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KIR2DS1

killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1

14 Gene Product Result for
Synonyms: CD158H CD158a p50.1
UniProtKB ID: Q14954, O43471
Gene ID:
Human(3806) Summary: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]
cow(493737) killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
Custom Gene Products
Our expertise in DNA & RNA oligo design, chemistry and manufacturing enable Sigma Custom Products to provide a comprehensive product portfolio. Learn more about our "custom capabilities & extensive options today."

shRNA

Type Description Species Add to Cart
 
SHCLNG-NM_014512 MISSION® shRNA Bacterial Glycerol Stock human pricing
SHCLND-NM_014512 MISSION® shRNA Plasmid DNA human pricing
SHCLNV-NM_014512 MISSION® shRNA Lentiviral Transduction Particles human pricing

Custom CRISPR Plasmid

Product # Description  
 
CRISPR Custom CRISPR Plasmid for gene knockout

siRNA

siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm.
All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product # siRNA Type Species  
 
NM_014512 Rosetta Predictions human pricing
siRNA
PRODUCT # siRNA Type ? SPECIES
NM_014512 Rosetta Predictions Human
Ranking siRNA ID Sequence Start ? Purification Size ? Price Select
1 SASI_Hs01_00145219 predicted 272
2 SASI_Hs01_00145220 predicted 371
3 SASI_Hs01_00145221 predicted 371
4 SASI_Hs01_00145222 predicted 375
5 SASI_Hs01_00145223 predicted 270
6 SASI_Hs01_00145224 predicted 423
7 SASI_Hs01_00145225 predicted 219
8 SASI_Hs01_00145226 predicted 171
9 SASI_Hs01_00145227 predicted 163
10 SASI_Hs01_00145228 predicted 628
shRNA
PRODUCT TYPE PRODUCT NAME SPECIES
SHCLNG-NM_014512
KIR2DS1 MISSION shRNA Bacterial Glycerol Stock
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
Human
6 Products Total
TRC Number Price Set Price (5+)? Select
TRCN0000056988    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-170s1c1
Sequence:CCGGGTCATGTTTGAACACTTCCTTCTCGAGAAGGAAGTGTTCAAACATGACTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000056990    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-887s1c1
Sequence:CCGGGATTCTGATGAACAAGACCATCTCGAGATGGTCTTGTTCATCAGAATCTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000056992    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-265s1c1
Sequence:CCGGCTTCTCCATCAGTCGCATGAACTCGAGTTCATGCGACTGATGGAGAAGTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000056991    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-123s1c1
Sequence:CCGGGCCTGGTGAAATCAGAAGAGACTCGAGTCTCTTCTGATTTCACCAGGCTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000056989    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-598s1c1
Sequence:CCGGCTACAGATGCTTCGGCTCTTTCTCGAGAAAGAGCCGAAGCATCTGTAGTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000430647    
Product Details

Region:CDS
TRC Version: 2 Clone ID:NM_014512.1-370s21c1
Sequence:CCGGCATCGTGATCATAGGTCTATACTCGAGTATAGACCTATGATCACGATGTTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
shRNA
PRODUCT TYPE PRODUCT NAME SPECIES
SHCLND-NM_014512
KIR2DS1 MISSION shRNA shRNA Plasmid DNA
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
Human
6 Products Total
TRC Number Vector Price Set Price (5+)? Select
TRCN0000056988    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-170s1c1
Sequence:CCGGGTCATGTTTGAACACTTCCTTCTCGAGAAGGAAGTGTTCAAACATGACTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000056990    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-887s1c1
Sequence:CCGGGATTCTGATGAACAAGACCATCTCGAGATGGTCTTGTTCATCAGAATCTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000056992    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-265s1c1
Sequence:CCGGCTTCTCCATCAGTCGCATGAACTCGAGTTCATGCGACTGATGGAGAAGTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000056991    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-123s1c1
Sequence:CCGGGCCTGGTGAAATCAGAAGAGACTCGAGTCTCTTCTGATTTCACCAGGCTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000056989    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-598s1c1
Sequence:CCGGCTACAGATGCTTCGGCTCTTTCTCGAGAAAGAGCCGAAGCATCTGTAGTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000430647    
Product Details

Region:CDS
TRC Version: 2 Clone ID:NM_014512.1-370s21c1
Sequence:CCGGCATCGTGATCATAGGTCTATACTCGAGTATAGACCTATGATCACGATGTTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
shRNA
PRODUCT TYPE PRODUCT NAME SPECIES
SHCLNV-NM_014512
KIR2DS1 MISSION shRNA Lentiviral Transduction Particles
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
Human
6 Products Total
TRC Number Volume Titer Vector Price Set Price (5+)? Select
TRCN0000056988    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-170s1c1
Sequence:CCGGGTCATGTTTGAACACTTCCTTCTCGAGAAGGAAGTGTTCAAACATGACTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000056990    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-887s1c1
Sequence:CCGGGATTCTGATGAACAAGACCATCTCGAGATGGTCTTGTTCATCAGAATCTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000056992    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-265s1c1
Sequence:CCGGCTTCTCCATCAGTCGCATGAACTCGAGTTCATGCGACTGATGGAGAAGTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000056991    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-123s1c1
Sequence:CCGGGCCTGGTGAAATCAGAAGAGACTCGAGTCTCTTCTGATTTCACCAGGCTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000056989    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_014512.1-598s1c1
Sequence:CCGGCTACAGATGCTTCGGCTCTTTCTCGAGAAAGAGCCGAAGCATCTGTAGTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000430647    
Product Details

Region:CDS
TRC Version: 2 Clone ID:NM_014512.1-370s21c1
Sequence:CCGGCATCGTGATCATAGGTCTATACTCGAGTATAGACCTATGATCACGATGTTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)