EMAIL THIS PAGE TO A FRIEND

KIR2DS2

killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2

10 Gene Product Result for
Synonyms: 183ActI CD158J CD158b NKAT5 cl-49
Species: Human KIR2DS2(100132285)
UniProtKB ID: P43631, Q14955, Q6H2G9
Gene ID:
Human(100132285) Summary: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]
Custom Gene Products
Our expertise in DNA & RNA oligo design, chemistry and manufacturing enable Sigma Custom Products to provide a comprehensive product portfolio. Learn more about our "custom capabilities & extensive options today."

Antibodies

Product # Description Species Reactivity Application Add to Cart
 
SAB1301062 ANTI-KIR2DS2 (CENTER) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution human
flow cytometry, immunohistochemistry, western blot pricing
SAB2700121 Anti-KIR2DS2 antibody produced in rabbit affinity isolated antibody, buffered aqueous solution human
immunohistochemistry, western blot pricing
SAB2700122 Anti-KIR2DS2 antibody produced in rabbit affinity isolated antibody, buffered aqueous solution human
immunofluorescence, immunohistochemistry, western blot pricing

shRNA

Type Description Species Add to Cart
 
SHCLNG-NM_012312 MISSION® shRNA Bacterial Glycerol Stock human pricing
SHCLND-NM_012312 MISSION® shRNA Plasmid DNA human pricing
SHCLNV-NM_012312 MISSION® shRNA Lentiviral Transduction Particles human pricing

Custom CRISPR Plasmid

Product # Description  
 
CRISPR Custom CRISPR Plasmid for gene knockout

siRNA

siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm.
All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product # siRNA Type Species  
 
NM_012312 Rosetta Predictions human pricing
siRNA
PRODUCT # siRNA Type ? SPECIES
NM_012312 Rosetta Predictions Human
Ranking siRNA ID Sequence Start ? Purification Size ? Price Select
1 SASI_Hs01_00106152 predicted 228
2 SASI_Hs01_00106153 predicted 174
3 SASI_Hs01_00106154 predicted 933
4 SASI_Hs01_00106155 predicted 225
5 SASI_Hs01_00106156 predicted 927
shRNA
PRODUCT TYPE PRODUCT NAME SPECIES
SHCLNG-NM_012312
KIR2DS2 MISSION shRNA Bacterial Glycerol Stock
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
Human
5 Products Total
TRC Number Price Set Price (5+)? Select
TRCN0000057029    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-376s1c1
Sequence:CCGGCATCGTCATCACAGGTCTATACTCGAGTATAGACCTGTGATGACGATGTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000057032    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-677s1c1
Sequence:CCGGGTCACAGGAAACCCTTCAAATCTCGAGATTTGAAGGGTTTCCTGTGACTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000057028    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-176s1c1
Sequence:CCGGGTCAGGTTTGAGCACTTCCTTCTCGAGAAGGAAGTGCTCAAACCTGACTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000057031    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-157s1c1
Sequence:CCGGCCTGCAATGTTGGTCAGATGTCTCGAGACATCTGACCAACATTGCAGGTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000057030    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-480s1c1
Sequence:CCGGCCTATGACATGTACCATCTATCTCGAGATAGATGGTACATGTCATAGGTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
shRNA
PRODUCT TYPE PRODUCT NAME SPECIES
SHCLND-NM_012312
KIR2DS2 MISSION shRNA shRNA Plasmid DNA
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
Human
5 Products Total
TRC Number Vector Price Set Price (5+)? Select
TRCN0000057029    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-376s1c1
Sequence:CCGGCATCGTCATCACAGGTCTATACTCGAGTATAGACCTGTGATGACGATGTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000057032    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-677s1c1
Sequence:CCGGGTCACAGGAAACCCTTCAAATCTCGAGATTTGAAGGGTTTCCTGTGACTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000057028    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-176s1c1
Sequence:CCGGGTCAGGTTTGAGCACTTCCTTCTCGAGAAGGAAGTGCTCAAACCTGACTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000057031    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-157s1c1
Sequence:CCGGCCTGCAATGTTGGTCAGATGTCTCGAGACATCTGACCAACATTGCAGGTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000057030    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-480s1c1
Sequence:CCGGCCTATGACATGTACCATCTATCTCGAGATAGATGGTACATGTCATAGGTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
shRNA
PRODUCT TYPE PRODUCT NAME SPECIES
SHCLNV-NM_012312
KIR2DS2 MISSION shRNA Lentiviral Transduction Particles
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
Human
5 Products Total
TRC Number Volume Titer Vector Price Set Price (5+)? Select
TRCN0000057029    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-376s1c1
Sequence:CCGGCATCGTCATCACAGGTCTATACTCGAGTATAGACCTGTGATGACGATGTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000057032    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-677s1c1
Sequence:CCGGGTCACAGGAAACCCTTCAAATCTCGAGATTTGAAGGGTTTCCTGTGACTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000057028    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-176s1c1
Sequence:CCGGGTCAGGTTTGAGCACTTCCTTCTCGAGAAGGAAGTGCTCAAACCTGACTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000057031    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-157s1c1
Sequence:CCGGCCTGCAATGTTGGTCAGATGTCTCGAGACATCTGACCAACATTGCAGGTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000057030    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012312.1-480s1c1
Sequence:CCGGCCTATGACATGTACCATCTATCTCGAGATAGATGGTACATGTCATAGGTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)