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KIR2DS3

killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3

10 Gene Product Result for
Synonyms: NKAT7
Species: Human KIR2DS3(3808)
UniProtKB ID: Q14952, O00644
Gene ID:
Human(3808) Summary: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]
Custom Gene Products
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shRNA

Type Description Species Add to Cart
 
SHCLNG-NM_012313 MISSION® shRNA Bacterial Glycerol Stock human pricing
SHCLND-NM_012313 MISSION® shRNA Plasmid DNA human pricing
SHCLNV-NM_012313 MISSION® shRNA Lentiviral Transduction Particles human pricing

Custom CRISPR Plasmid

Product # Description  
 
CRISPR Custom CRISPR Plasmid for gene knockout

siRNA

siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm.
All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product # siRNA Type Species  
 
NM_012313 Rosetta Predictions human pricing
siRNA
PRODUCT # siRNA Type ? SPECIES
NM_012313 Rosetta Predictions Human
Ranking siRNA ID Sequence Start ? Purification Size ? Price Select
1 SASI_Hs01_00037174 predicted 216
2 SASI_Hs01_00037175 predicted 213
3 SASI_Hs01_00037176 predicted 288
4 SASI_Hs01_00037177 predicted 204
5 SASI_Hs01_00037178 predicted 628
shRNA
PRODUCT TYPE PRODUCT NAME SPECIES
SHCLNG-NM_012313
KIR2DS3 MISSION shRNA Bacterial Glycerol Stock
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
Human
5 Products Total
TRC Number Price Set Price (5+)? Select
TRCN0000061714    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-868s1c1
Sequence:CCGGGAACAGTGAACAGGGAGGATTCTCGAGAATCCTCCCTGTTCACTGTTCTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000061713    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-168s1c1
Sequence:CCGGGTCATGTTTGAGCACTTCCTTCTCGAGAAGGAAGTGCTCAAACATGACTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000061717    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-905s1c1
Sequence:CCGGTCAGGAGGTGTCATACGCATACTCGAGTATGCGTATGACACCTCCTGATTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000061716    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-735s1c1
Sequence:CCGGAGACACCTACACGTTCTGATTCTCGAGAATCAGAACGTGTAGGTGTCTTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000061715    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-222s1c1
Sequence:CCGGCGCCTCATTGGAGAGCACATTCTCGAGAATGTGCTCTCCAATGAGGCGTTTTTG
Availability: Usually ships in 48 hours. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
shRNA
PRODUCT TYPE PRODUCT NAME SPECIES
SHCLND-NM_012313
KIR2DS3 MISSION shRNA shRNA Plasmid DNA
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
Human
5 Products Total
TRC Number Vector Price Set Price (5+)? Select
TRCN0000061714    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-868s1c1
Sequence:CCGGGAACAGTGAACAGGGAGGATTCTCGAGAATCCTCCCTGTTCACTGTTCTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000061713    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-168s1c1
Sequence:CCGGGTCATGTTTGAGCACTTCCTTCTCGAGAAGGAAGTGCTCAAACATGACTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000061717    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-905s1c1
Sequence:CCGGTCAGGAGGTGTCATACGCATACTCGAGTATGCGTATGACACCTCCTGATTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000061716    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-735s1c1
Sequence:CCGGAGACACCTACACGTTCTGATTCTCGAGAATCAGAACGTGTAGGTGTCTTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
TRCN0000061715    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-222s1c1
Sequence:CCGGCGCCTCATTGGAGAGCACATTCTCGAGAATGTGCTCTCCAATGAGGCGTTTTTG
Availability: Usually ships in 4 to 6 weeks. (Outside of the US and Europe, please allow an additional 1-2 weeks for delivery)
shRNA
PRODUCT TYPE PRODUCT NAME SPECIES
SHCLNV-NM_012313
KIR2DS3 MISSION shRNA Lentiviral Transduction Particles
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
Human
5 Products Total
TRC Number Volume Titer Vector Price Set Price (5+)? Select
TRCN0000061714    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-868s1c1
Sequence:CCGGGAACAGTGAACAGGGAGGATTCTCGAGAATCCTCCCTGTTCACTGTTCTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000061713    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-168s1c1
Sequence:CCGGGTCATGTTTGAGCACTTCCTTCTCGAGAAGGAAGTGCTCAAACATGACTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000061717    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-905s1c1
Sequence:CCGGTCAGGAGGTGTCATACGCATACTCGAGTATGCGTATGACACCTCCTGATTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000061716    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-735s1c1
Sequence:CCGGAGACACCTACACGTTCTGATTCTCGAGAATCAGAACGTGTAGGTGTCTTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
TRCN0000061715    
Product Details

Region:CDS
TRC Version: 1 Clone ID:NM_012313.1-222s1c1
Sequence:CCGGCGCCTCATTGGAGAGCACATTCTCGAGAATGTGCTCTCCAATGAGGCGTTTTTG
Availability: Usually Ships in 8 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)