Human(27257) Summary: This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011]
Mouse(67207) LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Rat(364624) LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Zebrafish(445157) LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
cow(535447) LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
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siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product #
siRNA Type
Species
NM_014462
Rosetta Predictions
human
pricing
NM_001108876
Rosetta Predictions
rat
pricing
NM_026032
Rosetta Predictions
mouse
pricing
XM_357867
Rosetta Predictions
mouse
pricing
XM_987686
Rosetta Predictions
mouse
pricing
shRNA
PRODUCT TYPE
PRODUCT NAME
SPECIES
SHCLNG-NM_014462
VALIDATED
LSM1 MISSION shRNA Bacterial Glycerol Stock LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Human
10 Products Total
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Price
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