Human(5229) Summary: Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]
Mouse(225467) protein geranylgeranyltransferase type I, beta subunit
Rat(81746) protein geranylgeranyltransferase type I, beta subunit
Zebrafish(570808) protein geranylgeranyltransferase type I, beta subunit
chicken(770633) protein geranylgeranyltransferase type I, beta subunit
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MISSION® siRNAs have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. The Rosetta-powered siRNA design algorithm has been optimized with over 3 years of continuous development for enhanced performance in RNAi applications. New and critical siRNA design rules incorporated into the latest algorithm lead to increased target specificity and knockdown for low abundance messages.
Validated MISSION® siRNAs have been functionally validated in Hela cells by Sigma scientists to Knockdown gene expression by 75% or greater. With Validated MISSION® siRNAs, we have done the upfront validation work, so that you do not have to.
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siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product #
siRNA Type
Species
NM_005023
Rosetta Predictions
human
pricing
NM_031082
Rosetta Predictions
rat
pricing
NM_172627
Rosetta Predictions
mouse
pricing
shRNA
PRODUCT TYPE
PRODUCT NAME
SPECIES
SHCLNG-NM_172627
VALIDATED
PGGT1B MISSION shRNA Bacterial Glycerol Stock protein geranylgeranyltransferase type I, beta subunit
Mouse
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