Human(292) Summary: This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]
Mouse(11740) solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
Rat(25176) solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
cow(282479) solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
sheep(100147788) solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
naked mole-rat(101697130) solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
domestic guinea pig(100722530) solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chicken(772225) solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
domestic cat(101082635) solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
dog(492093) solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
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MISSION® siRNAs have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. The Rosetta-powered siRNA design algorithm has been optimized with over 3 years of continuous development for enhanced performance in RNAi applications. New and critical siRNA design rules incorporated into the latest algorithm lead to increased target specificity and knockdown for low abundance messages.
Validated MISSION® siRNAs have been functionally validated in Hela cells by Sigma scientists to Knockdown gene expression by 75% or greater. With Validated MISSION® siRNAs, we have done the upfront validation work, so that you do not have to.
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siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product #
siRNA Type
Species
NM_001152
Rosetta Predictions
human
pricing
NM_057102
Rosetta Predictions
rat
pricing
shRNA
PRODUCT TYPE
PRODUCT NAME
SPECIES
SHCLNG-NM_007451
VALIDATED
SLC25A5 MISSION shRNA Bacterial Glycerol Stock solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
Mouse
10 Products Total
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Price
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