Human(2030) Summary: This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
Mouse(63959) solute carrier family 29 (nucleoside transporters), member 1
Rat(63997) solute carrier family 29 (equilibrative nucleoside transporter), member 1
cow(510932) solute carrier family 29 (nucleoside transporters), member 1
sheep(101117541) solute carrier family 29 (nucleoside transporters), member 1
Goat(100861005) solute carrier family 29 (nucleoside transporters), member 1
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MISSION® siRNAs have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. The Rosetta-powered siRNA design algorithm has been optimized with over 3 years of continuous development for enhanced performance in RNAi applications. New and critical siRNA design rules incorporated into the latest algorithm lead to increased target specificity and knockdown for low abundance messages.
Validated MISSION® siRNAs have been functionally validated in Hela cells by Sigma scientists to Knockdown gene expression by 75% or greater. With Validated MISSION® siRNAs, we have done the upfront validation work, so that you do not have to.
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siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product #
siRNA Type
Species
NM_001078174
Rosetta Predictions
human
pricing
NM_001078175
Rosetta Predictions
human
pricing
NM_001078176
Rosetta Predictions
human
pricing
NM_001078177
Rosetta Predictions
human
pricing
NM_004955
Rosetta Predictions
human
pricing
NM_031684
Rosetta Predictions
rat
pricing
NM_022880
Rosetta Predictions
mouse
pricing
shRNA
PRODUCT TYPE
PRODUCT NAME
SPECIES
SHCLNG-NM_022880
VALIDATED
SLC29A1 MISSION shRNA Bacterial Glycerol Stock solute carrier family 29 (equilibrative nucleoside transporter), member 1
Mouse
9 Products Total
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