Human(9066) Summary: This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
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MISSION® siRNAs have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. The Rosetta-powered siRNA design algorithm has been optimized with over 3 years of continuous development for enhanced performance in RNAi applications. New and critical siRNA design rules incorporated into the latest algorithm lead to increased target specificity and knockdown for low abundance messages.
Validated MISSION® siRNAs have been functionally validated in Hela cells by Sigma scientists to Knockdown gene expression by 75% or greater. With Validated MISSION® siRNAs, we have done the upfront validation work, so that you do not have to.
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siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product #
siRNA Type
Species
NM_004200
Rosetta Predictions
human
pricing
NM_021659
Rosetta Predictions
rat
pricing
NM_018801
Rosetta Predictions
mouse
pricing
NM_173067
Rosetta Predictions
mouse
pricing
NM_173068
Rosetta Predictions
mouse
pricing
shRNA
PRODUCT TYPE
PRODUCT NAME
SPECIES
SHCLNG-NM_004200
SYT7 MISSION shRNA Bacterial Glycerol Stock synaptotagmin VII
Human
12 Products Total
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