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MISSION® siRNAs have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. The Rosetta-powered siRNA design algorithm has been optimized with over 3 years of continuous development for enhanced performance in RNAi applications. New and critical siRNA design rules incorporated into the latest algorithm lead to increased target specificity and knockdown for low abundance messages.
Validated MISSION® siRNAs have been functionally validated in Hela cells by Sigma scientists to Knockdown gene expression by 75% or greater. With Validated MISSION® siRNAs, we have done the upfront validation work, so that you do not have to.
Custom Gene Products
Our expertise in DNA & RNA oligo design, chemistry and manufacturing enable Sigma Custom Products to provide a comprehensive product portfolio. Learn more about our "custom capabilities & extensive options today."
siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product #
siRNA Type
Species
NM_016281
siRNAs that have been validated in the lab
human
pricing
NM_001024254
Rosetta Predictions
rat
pricing
NM_001081308
Rosetta Predictions
mouse
pricing
XM_889805
Rosetta Predictions
mouse
pricing
XM_898640
Rosetta Predictions
mouse
pricing
XM_898648
Rosetta Predictions
mouse
pricing
XM_898654
Rosetta Predictions
mouse
pricing
XM_898662
Rosetta Predictions
mouse
pricing
XM_898669
Rosetta Predictions
mouse
pricing
XM_898685
Rosetta Predictions
mouse
pricing
XM_898693
Rosetta Predictions
mouse
pricing
shRNA
PRODUCT TYPE
PRODUCT NAME
SPECIES
SHCLNG-NM_016281
VALIDATED
TAOK3 MISSION shRNA Bacterial Glycerol Stock TAO kinase 3
Human
14 Products Total
TRC Number
Price
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