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TLR8

toll-like receptor 8

65 Gene Product Result for
Synonyms: CD288
UniProtKB ID: Q9NR97, B3Y654, Q495P4, Q6UXL6, Q9NYG9
Gene ID:
Human(51311) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008]
Mouse(170744) toll-like receptor 8
Rat(684440) toll-like receptor 8
Zebrafish(100334317) toll-like receptor 8
dog(100684828) toll-like receptor 8
Horse(100054367) toll-like receptor 8
domestic cat(493658) toll-like receptor 8
domestic guinea pig(100713058) toll-like receptor 8
naked mole-rat(101726643) toll-like receptor 8
Domestic Rabbit(100328930) toll-like receptor 8
cow(532262) toll-like receptor 8
sheep(554259) toll-like receptor 8
Goat(100860909) toll-like receptor 8
Custom Gene Products
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shRNA

Type Description Species Add to Cart
 

Custom CRISPR Plasmid

Product # Description  
 
CRISPR Custom CRISPR Plasmid for gene knockout

siRNA

siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm.
All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product # siRNA Type Species  
 
NM_016610 Rosetta Predictions human pricing
NM_138636 Rosetta Predictions human pricing
NM_001101009 Rosetta Predictions rat pricing
NM_133212 Rosetta Predictions mouse pricing
siRNA
PRODUCT # siRNA Type ? SPECIES
NM_016610 Rosetta Predictions Human
Ranking siRNA ID Sequence Start ?
1 SASI_Hs01_00064920 predicted 2481
2 SASI_Hs01_00064921 predicted 2679
3 SASI_Hs01_00064922 predicted 1987
4 SASI_Hs01_00064923 predicted 905
5 SASI_Hs01_00064924 predicted 2212
6 SASI_Hs01_00064925 predicted 626
7 SASI_Hs01_00064926 predicted 2655
8 SASI_Hs01_00064927 predicted 2366
9 SASI_Hs01_00064928 predicted 803
10 SASI_Hs01_00064929 predicted 2665
siRNA
PRODUCT # siRNA Type ? SPECIES
NM_138636 Rosetta Predictions Human
Ranking siRNA ID Sequence Start ?
1 SASI_Hs02_00363771 predicted 556
2 SASI_Hs02_00363772 predicted 1672
3 SASI_Hs01_00074144 predicted 2536
4 SASI_Hs01_00074146 predicted 763
5 SASI_Hs01_00074149 predicted 2512
6 SASI_Hs01_00074150 predicted 2225
7 SASI_Hs01_00074151 predicted 663
8 SASI_Hs01_00074152 predicted 2520
9 SASI_Hs02_00363773 predicted 2172
10 SASI_Hs02_00363774 predicted 1378
11 SASI_Hs01_00074143 predicted 2346
12 SASI_Hs01_00074145 predicted 1850
13 SASI_Hs01_00074147 predicted 2067
14 SASI_Hs01_00074148 predicted 490
siRNA
PRODUCT # siRNA Type ? SPECIES
NM_001101009 Rosetta Predictions Rat
Ranking siRNA ID Sequence Start ?
1 SASI_Rn02_00211216 predicted 770
2 SASI_Rn02_00211217 predicted 582
3 SASI_Rn02_00211218 predicted 1304
4 SASI_Rn02_00211219 predicted 2030
5 SASI_Rn02_00211220 predicted 2872
6 SASI_Rn02_00211221 predicted 2917
7 SASI_Rn02_00211222 predicted 2579
8 SASI_Rn02_00211223 predicted 2216
9 SASI_Rn02_00211224 predicted 1083
10 SASI_Rn02_00211225 predicted 942
siRNA
PRODUCT # siRNA Type ? SPECIES
NM_133212 Rosetta Predictions Mouse
Ranking siRNA ID Sequence Start ?
1 SASI_Mm01_00063246 predicted 671
2 SASI_Mm02_00338407 predicted 2230
3 SASI_Mm01_00063247 predicted 1273
4 SASI_Mm01_00063248 predicted 2773
5 SASI_Mm01_00063249 predicted 1208
6 SASI_Mm01_00063250 predicted 2388
7 SASI_Mm01_00063251 predicted 1120
8 SASI_Mm01_00063252 predicted 255
9 SASI_Mm01_00063254 predicted 2444
10 SASI_Mm02_00338408 predicted 1376
11 SASI_Mm01_00063245 predicted 510
12 SASI_Mm01_00063253 predicted 2147