Human(84959) Summary: This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. [provided by RefSeq, Jul 2008]
Mouse(72828) ubiquitin associated and SH3 domain containing, B
Rat(315579) ubiquitin associated and SH3 domain containing, B
chicken(419748) ubiquitin associated and SH3 domain containing B
dog(489355) ubiquitin associated and SH3 domain containing B
Horse(100063571) ubiquitin associated and SH3 domain containing B
cow(523809) ubiquitin associated and SH3 domain containing B
sheep(101111654) ubiquitin associated and SH3 domain containing B
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MISSION® siRNAs have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. The Rosetta-powered siRNA design algorithm has been optimized with over 3 years of continuous development for enhanced performance in RNAi applications. New and critical siRNA design rules incorporated into the latest algorithm lead to increased target specificity and knockdown for low abundance messages.
Validated MISSION® siRNAs have been functionally validated in Hela cells by Sigma scientists to Knockdown gene expression by 75% or greater. With Validated MISSION® siRNAs, we have done the upfront validation work, so that you do not have to.
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siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee.
Product #
siRNA Type
Species
NM_032873
Rosetta Predictions
human
pricing
XM_001065047
Rosetta Predictions
rat
pricing
XM_236104
Rosetta Predictions
rat
pricing
NM_176860
Rosetta Predictions
mouse
pricing
shRNA
PRODUCT TYPE
PRODUCT NAME
SPECIES
SHCLNG-NM_176860
VALIDATED
UBASH3B MISSION shRNA Bacterial Glycerol Stock ubiquitin associated and SH3 domain containing B
Mouse
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