Human(55245) Summary: This gene encodes a transmembrane protein that is structurally similar to the mouse basic fibroblast growth factor repressed ZIC-binding protein. In mouse this protein may be involved in fibroblast growth factor regulated growth control. In humans, polymorphisms in this gene are associated with variation in human height and osteoarthritis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Mouse(56046) ubiquinol-cytochrome c reductase complex chaperone, CBP3 homolog (yeast)
Rat(683512) ubiquinol-cytochrome c reductase complex chaperone
Zebrafish(767788) ubiquinol-cytochrome c reductase complex chaperone
dog(608882) ubiquinol-cytochrome c reductase complex chaperone
chicken(419139) ubiquinol-cytochrome c reductase complex chaperone
cow(618503) ubiquinol-cytochrome c reductase complex chaperone
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MISSION® siRNAs have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. The Rosetta-powered siRNA design algorithm has been optimized with over 3 years of continuous development for enhanced performance in RNAi applications. New and critical siRNA design rules incorporated into the latest algorithm lead to increased target specificity and knockdown for low abundance messages.
Validated MISSION® siRNAs have been functionally validated in Hela cells by Sigma scientists to Knockdown gene expression by 75% or greater. With Validated MISSION® siRNAs, we have done the upfront validation work, so that you do not have to.
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siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee.