Human(7381) Summary: This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X. [provided by RefSeq, Dec 2011]
Mouse(67530) ubiquinol-cytochrome c reductase binding protein
Rat(362897) ubiquinol-cytochrome c reductase binding protein
cow(616871) ubiquinol-cytochrome c reductase binding protein
chicken(420236) ubiquinol-cytochrome c reductase binding protein
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MISSION® siRNAs have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. The Rosetta-powered siRNA design algorithm has been optimized with over 3 years of continuous development for enhanced performance in RNAi applications. New and critical siRNA design rules incorporated into the latest algorithm lead to increased target specificity and knockdown for low abundance messages.
Validated MISSION® siRNAs have been functionally validated in Hela cells by Sigma scientists to Knockdown gene expression by 75% or greater. With Validated MISSION® siRNAs, we have done the upfront validation work, so that you do not have to.
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Product #
siRNA Type
Species
NM_006294
Rosetta Predictions
human
pricing
NM_001127553
Rosetta Predictions
rat
pricing
NM_026219
Rosetta Predictions
mouse
pricing
shRNA
PRODUCT TYPE
PRODUCT NAME
SPECIES
SHCLNG-NM_026219
VALIDATED
UQCRB MISSION shRNA Bacterial Glycerol Stock ubiquinol-cytochrome c reductase binding protein
Mouse
9 Products Total
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