EMAIL THIS PAGE TO A FRIEND

Organic letters

Enantioselective synthesis of the [6,6] spiroketal core of reveromycin A.


PMID 10814283

Abstract

[structure: see text] Reveromycin A (1) belongs to a family of microbial polyketides with unusual structural features and biological activities. The structure of 1 is composed of a [6,6] spiroketal core decorated with highly unsaturated side chains. As a prelude to the synthesis of 1, we present herein a short, efficient, and enantioselective synthesis of the C9-C21 fragment 5 (spiroketal core) of reveromycin A.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

R0654
Reveromycin A, solid
C36H52O11