EMAIL THIS PAGE TO A FRIEND

Current opinion in chemical biology

Bradykinin antagonists: new opportunities.


PMID 10959767

Abstract

The pro-inflammatory, pain producing, and cardiovascular effects of bradykinin B2 receptor activation are well characterized. Bradykinin B1 receptors also produce inflammation and pain. Therefore, antagonists are expected to be anti-inflammatory/analgesic drugs. Other exploitable clinical opportunities may exist. The newly discovered non-peptide B2 receptor antagonists and the equivalent B1 receptor pharmacological agents, which are in the pipeline, are suitable preclinical tools to properly evaluate potential utilities.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

H157
HOE 140, ≥94%
C59H89N19O13S