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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Plasticisation of amylodextrin by moisture. Consequences for compaction behaviour and tablet properties.


PMID 11576830

Abstract

Amylodextrin, a starch-based controlled release excipient, spontaneously absorbs moisture during storage. The aim of this study was to investigate plasticisation of amylodextrin by moisture and its effect on compaction and tablet characteristics. The glass transition temperature (T(g)) of amylodextrin powders with moisture fractions (x(w)) 0.070

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S9765
Starch, soluble, ACS reagent