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Natural product research

Morierinin: a new cytotoxic cucurbitacin from the leaves of Morierina montana Vieill.


PMID 12822899

Abstract

An extract of the leaves of Morierina montana collected in New Caledonia was found to be cytotoxic for KB cells. A bioassay-guided fractionation procedure led to the isolation of a series of cucurbitacins of which one, morierinin (1), is new. The isolation and structure elucidation of 1 are described.

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SML0577 Cucurbitacin E, ≥95% (HPLC)
C32H44O8