EMAIL THIS PAGE TO A FRIEND

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Retrograde tracing of zinc-containing neurons by selenide ions: a survey of seven selenium compounds.


PMID 1313065

Abstract

The autometallographic retrograde tracing of zinc-containing neurons by intracerebral injection of sodium selenite (Na2SeO3), introduced by Danscher in 1982, has recently been described in more detail. Intracerebral injections of both sodium selenide (Na2Se) and sodium selenite (Na2SeO3) have been successfully used; however, sodium selenite had a rather toxic effect on the injected tissue. In the present study, we tested seven different selenium compounds to find the most suitable compound for retrograde tracing of zinc-positive pathways. Among the tested compounds, sodium selenide (Na2Se) caused insignificant necrosis within the injection site and was easily transported retrogradely when handled anaerobically. Sodium selenide is therefore recommended as the compound of choice.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

323527
Selenium tetrachloride
Cl4Se