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Journal of biochemical and biophysical methods

Photochrome-labeling method in study of dynamics of biological systems.


PMID 1337353

Abstract

The theoretical considerations and experimental evidences discussed in this paper indicate that quantitative study of photochromic processes in labeled objects open up new possibilities for investigating microviscosity and conformation transitions in biological systems. The proposed method of photochrome labeling features higher sensitivity and simplicity, and uses labels which are more stable under physiological conditions compared with traditional spin labels.

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