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European psychiatry : the journal of the Association of European Psychiatrists

Lithium augmentation in venlafaxine non-responders: an open study.


PMID 14611927

Abstract

Thirteen major depressive patients not responding to a 4-week venlafaxine 300 mg treatment were eligible for a 4-week open trial of lithium addition. Two patients had to stop lithium for a possible moderate serotonin syndrome and five patients became responders, including one dramatic response and two semi-rapid responses.