EMAIL THIS PAGE TO A FRIEND

Yao xue xue bao = Acta pharmaceutica Sinica

[Isolation and structure identification of lignans from pine needles of pinus massoniana Lamb].


PMID 15040087

Abstract

To study the chemical constituents from the water-extracts of pine needles of Pinus massoniana Lamb. Chromatographic techniques were used to separate and purify compounds. Their physico-chemical properties and spectral data (UV, IR, MS, 1H-1H, 13C-1H NMR, DEPT, HMBC etc.) were used to elucidate the structures. Three lignans were isolated from the n-BuOH fraction of water-extracts. Their structures were identified as (7S,8R)-3',4,9'-tridihydroxy-4-methoxy- 9-O-shikimoyl-7,8-dihydrobenzofuran-1'-propylneolignan (massonianoid A, I), (7S,8R)-4,9-dihydroxy-3,3'-dimethoxy-7,8- dihydrobenzofuran-1'-propylneolignan (II) and 4,4',8-trihydroxy-4,4'-dimethoxy-9-lignanolide (III). Compound I is a new compound. While II and III were isolated from this plant for the first time.