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Biotechnology letters

High-yield conversion of (R)-2-octanol from the corresponding racemate by stereoinversion using Candida rugosa.


PMID 15685415

Abstract

Whole cells of Candida rugosa catalyzed the conversion of (R)-2-octanol from the corresponding racemate with the optical purity of 97% e.e. and yield of 92% in 10 h. The product was formed through a stereoinversion involving enantioselective oxidation and asymmetric reduction with 2-octanone as the intermediate.