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Yao xue xue bao = Acta pharmaceutica Sinica

[Alkaloids from the root of Lindera angustifolia].


PMID 16408812

Abstract

To study the alkaloid constituents of the root of Lindera angustifolia Cheng. The constituents were isolated and purified by column chromatography and the structures were characterized by spectral analysis. Seven aporphine alkaloids, laurotetanine (I), N-methyllaurotetanine (II), boldine (III), isoboldine (IV), norboldine (V), N-ethoxycarbonyllaurotetanine (VII) and a quaternary isoquinoline alkaloid, magnocurarine (VI), were isolated and identified. The structure of VII was further identified by semi-synthesis with I as starting material. All compounds were obtained from this plant for the first time and compound VII was found as a naturally occurring compound for the first time.

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