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Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

[Reaction of pyridinium salts with active methylene compounds].


PMID 16462100

Abstract

The carbon-carbon bond-forming reactions of 1-methyl-2-methylthiophenylpyridinium iodides with active methylene compounds (such as dimethyl malonate, malononitrile) using NaH as a base gave the 2-substituted methylene-1,2-dihydropyridine derivatives.

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